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    Crot carnitine O-octanoyltransferase [ Mus musculus (house mouse) ]

    Gene ID: 74114, updated on 31-Jan-2019

    Summary

    Official Symbol
    Crotprovided by MGI
    Official Full Name
    carnitine O-octanoyltransferaseprovided by MGI
    Primary source
    MGI:MGI:1921364
    See related
    Ensembl:ENSMUSG00000003623
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1200003H03Rik
    Expression
    Broad expression in liver adult (RPKM 39.3), liver E18 (RPKM 15.1) and 23 other tissues See more
    Orthologs

    Genomic context

    See Crot in Genome Data Viewer
    Location:
    5; 5 A1
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (8966033..8997146, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (8966048..8997146, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette, sub-family B (MDR/TAP), member 4 Neighboring gene calponin 3, acidic pseudogene Neighboring gene predicted gene, 31388 Neighboring gene coiled-coil domain-containing protein 72 pseudogene Neighboring gene predicted gene, 40264 Neighboring gene predicted gene, 31449

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    carnitine O-octanoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    carnitine O-octanoyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    carnitine O-octanoyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    carnitine metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    coenzyme A metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    fatty acid beta-oxidation ISO
    Inferred from Sequence Orthology
    more info
     
    fatty acid metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    fatty acid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    fatty acid transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    generation of precursor metabolites and energy ISO
    Inferred from Sequence Orthology
    more info
     
    lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    medium-chain fatty acid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    response to drug ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peroxisome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    peroxisome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    peroxisomal carnitine O-octanoyltransferase
    Names
    COT
    NP_076222.1
    XP_006503673.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023733.3NP_076222.1  peroxisomal carnitine O-octanoyltransferase

      See identical proteins and their annotated locations for NP_076222.1

      Status: PROVISIONAL

      Source sequence(s)
      AK004567
      Consensus CDS
      CCDS19087.1
      UniProtKB/Swiss-Prot
      Q9DC50
      Related
      ENSMUSP00000003720.4, ENSMUST00000003720.4
      Conserved Domains (1) summary
      pfam00755
      Location:20603
      Carn_acyltransf; Choline/Carnitine o-acyltransferase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      8966033..8997146 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503610.3XP_006503673.1  peroxisomal carnitine O-octanoyltransferase isoform X1

      Conserved Domains (1) summary
      pfam00755
      Location:151531
      Carn_acyltransf; Choline/Carnitine o-acyltransferase
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