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    Rbm19 RNA binding motif protein 19 [ Mus musculus (house mouse) ]

    Gene ID: 74111, updated on 2-Nov-2024

    Summary

    Official Symbol
    Rbm19provided by MGI
    Official Full Name
    RNA binding motif protein 19provided by MGI
    Primary source
    MGI:MGI:1921361
    See related
    Ensembl:ENSMUSG00000029594 AllianceGenome:MGI:1921361
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NPO; 1200009A02Rik
    Summary
    Predicted to enable RNA binding activity. Involved in positive regulation of embryonic development. Located in cytoplasm; nucleolus; and nucleoplasm. Is expressed in brain and gut. Orthologous to human RBM19 (RNA binding motif protein 19). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 4.9), ovary adult (RPKM 4.5) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rbm19 in Genome Data Viewer
    Location:
    5 F; 5 60.58 cM
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (120254578..120337036)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (120116513..120198971)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42018 Neighboring gene predicted gene, 42019 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:120556460-120556643 Neighboring gene STARR-seq mESC enhancer starr_14232 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:120575005-120575261 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:120575328-120575529 Neighboring gene VISTA enhancer mm144 Neighboring gene predicted gene 10390 Neighboring gene predicted gene, 31836 Neighboring gene STARR-seq mESC enhancer starr_14234 Neighboring gene LIM homeobox 5, antisense 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA0682

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nuclear speck IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    probable RNA-binding protein 19

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028762.1NP_083038.1  probable RNA-binding protein 19

      See identical proteins and their annotated locations for NP_083038.1

      Status: PROVISIONAL

      Source sequence(s)
      BC025619
      Consensus CDS
      CCDS19616.1
      UniProtKB/Swiss-Prot
      Q8BHR0, Q8R3C6, Q9CW63
      UniProtKB/TrEMBL
      A0A0J9YUT8
      Related
      ENSMUSP00000031590.9, ENSMUST00000031590.12
      Conserved Domains (8) summary
      COG0724
      Location:2183
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12318
      Location:722801
      RRM5_RBM19_like; RNA recognition motif 5 in RNA-binding protein 19 (RBM19 or RBD-1) and similar proteins
      cd12502
      Location:293364
      RRM2_RMB19; RNA recognition motif 2 in RNA-binding protein 19 (RBM19) and similar proteins
      cd12564
      Location:277
      RRM1_RBM19; RNA recognition motif 1 in RNA-binding protein 19 (RBM19) and similar proteins
      cd12567
      Location:398476
      RRM3_RBM19; RNA recognition motif 3 in RNA-binding protein 19 (RBM19) and similar proteins
      cd12569
      Location:584655
      RRM4_RBM19; RNA recognition motif 4 in RNA-binding protein 19 (RBM19) and similar proteins
      cd12571
      Location:824902
      RRM6_RBM19; RNA recognition motif 6 in RNA-binding protein 19 (RBM19) and similar proteins
      TIGR01661
      Location:402798
      ELAV_HUD_SF; ELAV/HuD family splicing factor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      120254578..120337036
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)