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    Cep55 centrosomal protein 55 [ Mus musculus (house mouse) ]

    Gene ID: 74107, updated on 6-Sep-2021

    Summary

    Official Symbol
    Cep55provided by MGI
    Official Full Name
    centrosomal protein 55provided by MGI
    Primary source
    MGI:MGI:1921357
    See related
    Ensembl:ENSMUSG00000024989
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1200008O12Rik; 2700032M20Rik
    Expression
    Biased expression in CNS E11.5 (RPKM 14.2), placenta adult (RPKM 6.0) and 11 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Cep55 in Genome Data Viewer
    Location:
    19; 19 C2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (38043423..38062873)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (38054970..38074425)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (38129515..38148915)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene myoferlin Neighboring gene predicted gene, 52397 Neighboring gene predicted gene, 52396 Neighboring gene predicted gene, 23300 Neighboring gene free fatty acid receptor 4 Neighboring gene retinol binding protein 4, plasma

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cranial skeletal system development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in establishment of protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in midbody abscission ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of phosphatidylinositol 3-kinase signaling IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Flemming body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intercellular bridge IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in midbody IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    centrosomal protein of 55 kDa

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164362.2NP_001157834.1  centrosomal protein of 55 kDa isoform 1

      See identical proteins and their annotated locations for NP_001157834.1

      Status: VALIDATED

      Source sequence(s)
      AC101774, AK004655, AW538141
      Consensus CDS
      CCDS50429.1
      UniProtKB/Swiss-Prot
      Q8BT07
      Related
      ENSMUSP00000127961.2, ENSMUST00000169673.3
      Conserved Domains (2) summary
      COG1196
      Location:58397
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:171204
      EABR; TSG101 and ALIX binding domain of CEP55
    2. NM_001360663.1NP_001347592.1  centrosomal protein of 55 kDa isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC101774
      Consensus CDS
      CCDS50429.1
      Related
      ENSMUSP00000157898.2, ENSMUST00000236044.2
      Conserved Domains (2) summary
      COG1196
      Location:58397
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:171204
      EABR; TSG101 and ALIX binding domain of CEP55
    3. NM_028293.2NP_082569.1  centrosomal protein of 55 kDa isoform 1

      See identical proteins and their annotated locations for NP_082569.1

      Status: VALIDATED

      Source sequence(s)
      AC101774, AK004655, AK028216, AW538141, CJ074252
      Consensus CDS
      CCDS50429.1
      UniProtKB/Swiss-Prot
      Q8BT07
      Related
      ENSMUSP00000093802.5, ENSMUST00000096096.12
      Conserved Domains (2) summary
      COG1196
      Location:58397
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:171204
      EABR; TSG101 and ALIX binding domain of CEP55
    4. NM_028760.3NP_083036.2  centrosomal protein of 55 kDa isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC101774, AK004655, AW538141
      Consensus CDS
      CCDS29782.1
      UniProtKB/Swiss-Prot
      Q8BT07
      Related
      ENSMUSP00000157871.2, ENSMUST00000237408.2
      Conserved Domains (2) summary
      pfam12180
      Location:171204
      EABR; TSG101 and ALIX binding domain of CEP55
      cl19219
      Location:256332
      DUF342; Protein of unknown function (DUF342)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      38043423..38062873
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527396.3XP_006527459.1  centrosomal protein of 55 kDa isoform X1

      See identical proteins and their annotated locations for XP_006527459.1

      UniProtKB/Swiss-Prot
      Q8BT07
      Conserved Domains (2) summary
      COG1196
      Location:58397
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:171204
      EABR; TSG101 and ALIX binding domain of CEP55
    2. XM_006527399.4XP_006527462.1  centrosomal protein of 55 kDa isoform X1

      See identical proteins and their annotated locations for XP_006527462.1

      UniProtKB/Swiss-Prot
      Q8BT07
      Conserved Domains (2) summary
      COG1196
      Location:58397
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:171204
      EABR; TSG101 and ALIX binding domain of CEP55
    3. XM_006527401.2XP_006527464.1  centrosomal protein of 55 kDa isoform X1

      See identical proteins and their annotated locations for XP_006527464.1

      UniProtKB/Swiss-Prot
      Q8BT07
      Conserved Domains (2) summary
      COG1196
      Location:58397
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:171204
      EABR; TSG101 and ALIX binding domain of CEP55
    4. XM_030251115.2XP_030106975.1  centrosomal protein of 55 kDa isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:78244
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:1750
      EABR; TSG101 and ALIX binding domain of CEP55
    5. XM_006527402.3XP_006527465.1  centrosomal protein of 55 kDa isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:78244
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:1750
      EABR; TSG101 and ALIX binding domain of CEP55
    6. XM_030251114.2XP_030106974.1  centrosomal protein of 55 kDa isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:78244
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:1750
      EABR; TSG101 and ALIX binding domain of CEP55
    7. XM_006527397.5XP_006527460.1  centrosomal protein of 55 kDa isoform X1

      See identical proteins and their annotated locations for XP_006527460.1

      UniProtKB/Swiss-Prot
      Q8BT07
      Conserved Domains (2) summary
      COG1196
      Location:58397
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:171204
      EABR; TSG101 and ALIX binding domain of CEP55
    8. XM_011247381.4XP_011245683.1  centrosomal protein of 55 kDa isoform X1

      See identical proteins and their annotated locations for XP_011245683.1

      UniProtKB/Swiss-Prot
      Q8BT07
      Conserved Domains (2) summary
      COG1196
      Location:58397
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:171204
      EABR; TSG101 and ALIX binding domain of CEP55
    9. XM_006527398.5XP_006527461.1  centrosomal protein of 55 kDa isoform X1

      See identical proteins and their annotated locations for XP_006527461.1

      UniProtKB/Swiss-Prot
      Q8BT07
      Conserved Domains (2) summary
      COG1196
      Location:58397
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:171204
      EABR; TSG101 and ALIX binding domain of CEP55
    10. XM_036161710.1XP_036017603.1  centrosomal protein of 55 kDa isoform X1

      Conserved Domains (2) summary
      COG1196
      Location:58397
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:171204
      EABR; TSG101 and ALIX binding domain of CEP55
    11. XM_036161711.1XP_036017604.1  centrosomal protein of 55 kDa isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:78244
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:1750
      EABR; TSG101 and ALIX binding domain of CEP55
    12. XM_030251113.2XP_030106973.1  centrosomal protein of 55 kDa isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:78244
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:1750
      EABR; TSG101 and ALIX binding domain of CEP55
    13. XM_036161712.1XP_036017605.1  centrosomal protein of 55 kDa isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:78244
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12180
      Location:1750
      EABR; TSG101 and ALIX binding domain of CEP55
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