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    Abcb6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 [ Mus musculus (house mouse) ]

    Gene ID: 74104, updated on 3-Feb-2019

    Summary

    Official Symbol
    Abcb6provided by MGI
    Official Full Name
    ATP-binding cassette, sub-family B (MDR/TAP), member 6provided by MGI
    Primary source
    MGI:MGI:1921354
    See related
    Ensembl:ENSMUSG00000026198
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1200005B17Rik
    Expression
    Ubiquitous expression in liver adult (RPKM 38.1), colon adult (RPKM 25.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Abcb6 in Genome Data Viewer
    Location:
    1; 1 C4
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (75171640..75180392, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (75168214..75176857, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene reticulophagy regulator family member 2 Neighboring gene zinc finger, AN1 type domain 2B Neighboring gene autophagy related 9A Neighboring gene ankyrin repeat and zinc finger domain containing 1 Neighboring gene galactosidase, beta 1-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    ATPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity, coupled to transmembrane movement of substances IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    efflux transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    heme binding ISO
    Inferred from Sequence Orthology
    more info
     
    heme-transporting ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    brain development ISO
    Inferred from Sequence Orthology
    more info
     
    heme transport ISO
    Inferred from Sequence Orthology
    more info
     
    porphyrin-containing compound biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    skin development ISO
    Inferred from Sequence Orthology
    more info
     
    transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial envelope ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    vacuolar membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    ATP-binding cassette sub-family B member 6, mitochondrial

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023732.3NP_076221.1  ATP-binding cassette sub-family B member 6, mitochondrial

      See identical proteins and their annotated locations for NP_076221.1

      Status: VALIDATED

      Source sequence(s)
      AC166150, AI843102, AK004605, AK151165
      Consensus CDS
      CCDS15065.1
      UniProtKB/Swiss-Prot
      Q9DC29
      Related
      ENSMUSP00000027396.8, ENSMUST00000027396.14
      Conserved Domains (4) summary
      cd03253
      Location:590825
      ABCC_ATM1_transporter; ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C
      COG5265
      Location:329823
      ATM1; ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]
      pfam16185
      Location:6255
      MTABC_N; Mitochondrial ABC-transporter N-terminal five TM region
      cl00549
      Location:277544
      ABC_membrane; ABC transporter transmembrane region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      75171640..75180392 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496552.2XP_006496615.1  ATP-binding cassette sub-family B member 6, mitochondrial isoform X1

      Conserved Domains (3) summary
      cd03253
      Location:302537
      ABCC_ATM1_transporter; ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C
      COG5265
      Location:41535
      ATM1; ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]
      cl00549
      Location:6256
      ABC_membrane; ABC transporter transmembrane region
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