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    Asz1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 74068, updated on 23-Jun-2021

    Summary

    Official Symbol
    Asz1provided by MGI
    Official Full Name
    ankyrin repeat, SAM and basic leucine zipper domain containing 1provided by MGI
    Primary source
    MGI:MGI:1921318
    See related
    Ensembl:ENSMUSG00000010796
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ga; Gasz; ORF3; 4933400N19Rik
    Expression
    Biased expression in bladder adult (RPKM 3.4), testis adult (RPKM 3.0) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Asz1 in Genome Data Viewer
    Location:
    6; 6 A2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (18050963..18109060, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (18050964..18109061, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (18000964..18059061, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene suppression of tumorigenicity 7 Neighboring gene predicted gene, 52895 Neighboring gene wingless-type MMTV integration site family, member 2 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene NSA2 ribosome biogenesis homolog pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA methylation involved in gamete generation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within gene silencing by RNA IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in germ cell development NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in male meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in piRNA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in piRNA metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    is_active_in pi-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in pi-body IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
    Names
    germ cell-specific ankyrin, SAM and basic leucine zipper domain containing protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023729.3NP_076218.3  ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

      See identical proteins and their annotated locations for NP_076218.3

      Status: VALIDATED

      Source sequence(s)
      AF459789, BB020038, BC058859, BG088136
      Consensus CDS
      CCDS19929.1
      UniProtKB/Swiss-Prot
      Q8VD46
      Related
      ENSMUSP00000010940.5, ENSMUST00000010940.11
      Conserved Domains (6) summary
      cd09521
      Location:273333
      SAM_ASZ1; SAM domain of ASZ1 subfamily
      cd00204
      Location:77202
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:83179
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:4799
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:168222
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:151179
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      18050963..18109060 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505176.3XP_006505239.1  ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006505239.1

      Conserved Domains (3) summary
      cd09521
      Location:124184
      SAM_ASZ1; SAM domain of ASZ1 subfamily
      sd00045
      Location:230
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:485
      Ank_2; Ankyrin repeats (3 copies)
    2. XM_006505178.3XP_006505241.1  ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006505241.1

      Conserved Domains (3) summary
      cd09521
      Location:124184
      SAM_ASZ1; SAM domain of ASZ1 subfamily
      sd00045
      Location:230
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:485
      Ank_2; Ankyrin repeats (3 copies)
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