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    Mcee methylmalonyl CoA epimerase [ Mus musculus (house mouse) ]

    Gene ID: 73724, updated on 18-Sep-2024

    Summary

    Official Symbol
    Mceeprovided by MGI
    Official Full Name
    methylmalonyl CoA epimeraseprovided by MGI
    Primary source
    MGI:MGI:1920974
    See related
    Ensembl:ENSMUSG00000033429 AllianceGenome:MGI:1920974
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110007A04Rik
    Summary
    Predicted to enable methylmalonyl-CoA epimerase activity. Predicted to be involved in L-methylmalonyl-CoA metabolic process. Located in mitochondrion. Is expressed in central nervous system; choroid plexus; and nervous system. Orthologous to human MCEE (methylmalonyl-CoA epimerase). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in heart adult (RPKM 21.9), kidney adult (RPKM 21.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Mcee in Genome Data Viewer
    Location:
    7 34.65 cM; 7 C
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (64042370..64061869)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (64392622..64412121)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_19038 Neighboring gene STARR-seq mESC enhancer starr_19039 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:71537088-71537271 Neighboring gene STARR-positive B cell enhancer ABC_E4931 Neighboring gene M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) Neighboring gene SET translocation pseudogene Neighboring gene FANCD2/FANCI-associated nuclease 1 Neighboring gene STARR-seq mESC enhancer starr_19041 Neighboring gene amyloid beta precursor protein binding family A member 2 Neighboring gene STARR-seq mESC enhancer starr_19042 Neighboring gene STARR-seq mESC enhancer starr_19043 Neighboring gene endosomal transmembrane epsin interactor 2 Neighboring gene STARR-seq mESC enhancer starr_19044 Neighboring gene STARR-seq mESC enhancer starr_19045 Neighboring gene NSE3 homolog, SMC5-SMC6 complex component

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Pathways from PubChem

    General protein information

    Preferred Names
    methylmalonyl-CoA epimerase, mitochondrial
    Names
    DL-methylmalonyl-CoA racemase
    NP_001342053.1
    NP_082902.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355124.1NP_001342053.1  methylmalonyl-CoA epimerase, mitochondrial isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC129199
      Consensus CDS
      CCDS90248.1
      UniProtKB/TrEMBL
      A0A0U1RQ27
      Related
      ENSMUSP00000146220.2, ENSMUST00000206194.2
      Conserved Domains (1) summary
      cl14632
      Location:49123
      VOC; vicinal oxygen chelate (VOC) family
    2. NM_028626.2NP_082902.1  methylmalonyl-CoA epimerase, mitochondrial isoform 1 precursor

      See identical proteins and their annotated locations for NP_082902.1

      Status: VALIDATED

      Source sequence(s)
      AC129199
      Consensus CDS
      CCDS21334.1
      UniProtKB/Swiss-Prot
      Q9D1I5
      Related
      ENSMUSP00000047855.9, ENSMUST00000037205.11
      Conserved Domains (1) summary
      TIGR03081
      Location:49177
      metmalonyl_epim; methylmalonyl-CoA epimerase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      64042370..64061869
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)