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    Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 [ Mus musculus (house mouse) ]

    Gene ID: 73723, updated on 27-Nov-2024

    Summary

    Official Symbol
    Sh3bgrl3provided by MGI
    Official Full Name
    SH3 domain binding glutamic acid-rich protein-like 3provided by MGI
    Primary source
    MGI:MGI:1920973
    See related
    Ensembl:ENSMUSG00000028843 AllianceGenome:MGI:1920973
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110004L05Rik
    Summary
    Predicted to be involved in cytoskeleton organization. Predicted to be located in cytosol; nuclear body; and ruffle membrane. Predicted to be active in cytoplasm. Is expressed in nervous system and thymus primordium. Orthologous to human SH3BGRL3 (SH3 domain binding glutamate rich protein like 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in spleen adult (RPKM 411.7), thymus adult (RPKM 259.5) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Sh3bgrl3 in Genome Data Viewer
    Location:
    4 D2.3; 4 66.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (133854717..133856044, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134127406..134128733, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9600 Neighboring gene STARR-positive B cell enhancer ABC_E842 Neighboring gene STARR-positive B cell enhancer ABC_E4678 Neighboring gene STARR-positive B cell enhancer ABC_E10264 Neighboring gene CD52 antigen Neighboring gene UBX domain protein 11 Neighboring gene STARR-seq mESC enhancer starr_11667 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:133677585-133677803 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:133680177-133680360 Neighboring gene centrosomal protein 85 Neighboring gene STARR-positive B cell enhancer mm9_chr4:133715471-133715771 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:133742713-133742822 Neighboring gene STARR-positive B cell enhancer ABC_E843 Neighboring gene zona pellucida like domain containing 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ruffle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ruffle membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    SH3 domain-binding glutamic acid-rich-like protein 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_080559.2NP_542126.1  SH3 domain-binding glutamic acid-rich-like protein 3

      See identical proteins and their annotated locations for NP_542126.1

      Status: VALIDATED

      Source sequence(s)
      AL670680
      Consensus CDS
      CCDS38910.1
      UniProtKB/Swiss-Prot
      Q91VW3
      Related
      ENSMUSP00000030651.9, ENSMUST00000030651.9
      Conserved Domains (1) summary
      pfam04908
      Location:293
      SH3BGR; SH3-binding, glutamic acid-rich protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      133854717..133856044 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)