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    Dppa4 developmental pluripotency associated 4 [ Mus musculus (house mouse) ]

    Gene ID: 73693, updated on 19-Mar-2019

    Summary

    Official Symbol
    Dppa4provided by MGI
    Official Full Name
    developmental pluripotency associated 4provided by MGI
    Primary source
    MGI:MGI:2157525
    See related
    Ensembl:ENSMUSG00000058550
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C76608; ECAT15-1; 2410091M23Rik
    Expression
    Low expression observed in reference dataset See more
    Orthologs

    Genomic context

    See Dppa4 in Genome Data Viewer
    Location:
    16; 16 B5
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (48283735..48294292)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (48283848..48294405)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 6430553K19 gene Neighboring gene peroxiredoxin 1 pseudogene Neighboring gene developmental pluripotency associated 2 Neighboring gene predicted gene 5485

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    • PluriNetWork, organism-specific biosystem (from WikiPathways)
      PluriNetWork, organism-specific biosystemThe aim of the PluriNetWork is to give an overview of specific mechanisms associated with pluripotency in mouse. Each node represents a gene and its corresponding protein product. As stated, we inten...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    chromatin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    lung-associated mesenchyme development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    lung-associated mesenchyme development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    developmental pluripotency-associated protein 4
    Names
    embryonic stem cell-associated transcript 15-1 protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001018002.1NP_001018002.1  developmental pluripotency-associated protein 4 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame segment in the coding region, as compared to variant 1. The encoded isoform (2) thus lacks an internal segment compared to isoform 1.
      Source sequence(s)
      AK033197, BY731814, CAAA01133063
      Consensus CDS
      CCDS28208.1
      UniProtKB/Swiss-Prot
      Q8CCG4
      UniProtKB/TrEMBL
      E9PUG8
      Related
      ENSMUSP00000093748.1, ENSMUST00000050705.3
      Conserved Domains (2) summary
      pfam14047
      Location:169235
      DCR; Dppa2/4 conserved region
      pfam14049
      Location:73157
      Dppa2_A; Dppa2/4 conserved region in higher vertebrates
    2. NM_028610.2NP_082886.2  developmental pluripotency-associated protein 4 isoform 1

      See identical proteins and their annotated locations for NP_082886.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK033197, BC064754, CAAA01133063
      Consensus CDS
      CCDS28209.1
      UniProtKB/Swiss-Prot
      Q8CCG4
      Related
      ENSMUSP00000093749.1, ENSMUST00000096045.8
      Conserved Domains (2) summary
      pfam14047
      Location:221287
      DCR; Dppa2/4 conserved region
      pfam14049
      Location:125209
      Dppa2_A; Dppa2/4 conserved region in higher vertebrates

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      48283735..48294292
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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