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    Thoc3 THO complex 3 [ Mus musculus (house mouse) ]

    Gene ID: 73666, updated on 23-Jun-2021

    Summary

    Official Symbol
    Thoc3provided by MGI
    Official Full Name
    THO complex 3provided by MGI
    Primary source
    MGI:MGI:1920916
    See related
    Ensembl:ENSMUSG00000025872
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AL033344; 2410044K02Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 21.8), CNS E14 (RPKM 12.9) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Thoc3 in Genome Data Viewer
    Location:
    13; 13 B1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (54606650..54616653, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (54458837..54468840, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (54560198..54570201, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40955 Neighboring gene predicted gene, 48622 Neighboring gene complexin 2 Neighboring gene predicted gene, 53205 Neighboring gene predicted gene 2830 Neighboring gene SUMO-interacting motifs containing 1 Neighboring gene RIKEN cDNA 4833439L19 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mRNA export from nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in viral mRNA export from host cell nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of THO complex part of transcription export complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of THO complex part of transcription export complex ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with chromosome, telomeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of transcription export complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    THO complex subunit 3
    Names
    tho3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028597.3NP_082873.2  THO complex subunit 3

      See identical proteins and their annotated locations for NP_082873.2

      Status: VALIDATED

      Source sequence(s)
      AC165145
      Consensus CDS
      CCDS26527.1
      UniProtKB/Swiss-Prot
      Q8VE80
      Related
      ENSMUSP00000026990.6, ENSMUST00000026990.6
      Conserved Domains (3) summary
      COG2319
      Location:46329
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:49290
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:5997
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      54606650..54616653 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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