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    Rnf38 ring finger protein 38 [ Mus musculus (house mouse) ]

    Gene ID: 73469, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rnf38provided by MGI
    Official Full Name
    ring finger protein 38provided by MGI
    Primary source
    MGI:MGI:1920719
    See related
    Ensembl:ENSMUSG00000035696
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    O; Oip1; AA673263; 1700065B19Rik; 2610202O07Rik
    Expression
    Broad expression in testis adult (RPKM 139.9), whole brain E14.5 (RPKM 39.1) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Rnf38 in Genome Data Viewer
    Location:
    4; 4 B1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (44126210..44233929, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (44126210..44233905, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (44139084..44181155, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Neighboring gene prothymosin alpha, pseudogene 2 Neighboring gene microRNA 5106 Neighboring gene predicted gene, 54218 Neighboring gene maternal embryonic leucine zipper kinase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sperm flagellum ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase RNF38
    Names
    RING-type E3 ubiquitin transferase RNF38
    NP_001034082.1
    NP_001342110.1
    NP_001366503.1
    NP_001366504.1
    NP_001366505.1
    NP_001366506.1
    NP_001366507.1
    NP_001366508.1
    NP_001366509.1
    NP_001366510.1
    NP_780410.2
    XP_006538363.1
    XP_006538364.1
    XP_006538368.1
    XP_011248417.2
    XP_011248418.2
    XP_011248419.2
    XP_030109694.1
    XP_036020382.1
    XP_036020383.1
    XP_036020384.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038993.5NP_001034082.1  E3 ubiquitin-protein ligase RNF38 isoform 2

      See identical proteins and their annotated locations for NP_001034082.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2), as well as variants 3-8, encodes isoform 2.
      Source sequence(s)
      AL732563, AL805952
      Consensus CDS
      CCDS18123.1
      UniProtKB/TrEMBL
      Q3UH35
      Related
      ENSMUSP00000038477.9, ENSMUST00000045793.15
      Conserved Domains (1) summary
      cd16472
      Location:377421
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    2. NM_001355181.2NP_001342110.1  E3 ubiquitin-protein ligase RNF38 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variants 2 and 4-8, encodes isoform 2.
      Source sequence(s)
      AL732563, AL805952
      Consensus CDS
      CCDS18123.1
      Conserved Domains (1) summary
      cd16472
      Location:377421
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    3. NM_001379574.1NP_001366503.1  E3 ubiquitin-protein ligase RNF38 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), as well as variants 2, 3, and 5-8, encodes isoform 2.
      Source sequence(s)
      AL732563, AL805952
      Conserved Domains (1) summary
      cd16472
      Location:377421
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    4. NM_001379575.1NP_001366504.1  E3 ubiquitin-protein ligase RNF38 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5), as well as variants 2-4 and 6-8, encodes isoform 2.
      Source sequence(s)
      AL732563, AL805952
      Conserved Domains (1) summary
      cd16472
      Location:377421
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    5. NM_001379576.1NP_001366505.1  E3 ubiquitin-protein ligase RNF38 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6), as well as variants 2-5, 7, and 8, encodes isoform 2.
      Source sequence(s)
      AL732563, AL805952
      Conserved Domains (1) summary
      cd16472
      Location:377421
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    6. NM_001379577.1NP_001366506.1  E3 ubiquitin-protein ligase RNF38 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variants 2-6 and 8, encodes isoform 2.
      Source sequence(s)
      AL732563, AL805952
      Related
      ENSMUSP00000099998.3, ENSMUST00000102934.9
      Conserved Domains (1) summary
      cd16472
      Location:377421
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    7. NM_001379578.1NP_001366507.1  E3 ubiquitin-protein ligase RNF38 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8), as well as variants 2-7, encodes isoform 2.
      Source sequence(s)
      AL732563, AL805952
      Conserved Domains (1) summary
      cd16472
      Location:377421
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    8. NM_001379579.1NP_001366508.1  E3 ubiquitin-protein ligase RNF38 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) represents the longest transcript and encodes the longest isoform (3).
      Source sequence(s)
      AL732563, AL805952
      Conserved Domains (1) summary
      cd16472
      Location:522566
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    9. NM_001379580.1NP_001366509.1  E3 ubiquitin-protein ligase RNF38 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL732563, AL805952
      Conserved Domains (1) summary
      cd16472
      Location:518562
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    10. NM_001379581.1NP_001366510.1  E3 ubiquitin-protein ligase RNF38 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL732563, AL805952
      Conserved Domains (1) summary
      cd16472
      Location:459503
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    11. NM_175201.7NP_780410.2  E3 ubiquitin-protein ligase RNF38 isoform 1

      See identical proteins and their annotated locations for NP_780410.2

      Status: VALIDATED

      Source sequence(s)
      AL732563, AL805952
      Consensus CDS
      CCDS18122.1
      UniProtKB/Swiss-Prot
      Q8BI21
      Related
      ENSMUSP00000095702.3, ENSMUST00000098098.9
      Conserved Domains (1) summary
      cd16472
      Location:409453
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      44126210..44233929 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250115.4XP_011248417.2  E3 ubiquitin-protein ligase RNF38 isoform X1

      Conserved Domains (1) summary
      cd16472
      Location:568612
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    2. XM_011250117.4XP_011248419.2  E3 ubiquitin-protein ligase RNF38 isoform X4

      Conserved Domains (1) summary
      cd16472
      Location:534578
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    3. XM_011250116.4XP_011248418.2  E3 ubiquitin-protein ligase RNF38 isoform X2

      Conserved Domains (1) summary
      cd16472
      Location:539583
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    4. XM_036164489.1XP_036020382.1  E3 ubiquitin-protein ligase RNF38 isoform X7

      Conserved Domains (1) summary
      cd16472
      Location:377421
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    5. XM_036164490.1XP_036020383.1  E3 ubiquitin-protein ligase RNF38 isoform X7

      Conserved Domains (1) summary
      cd16472
      Location:377421
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    6. XM_030253834.2XP_030109694.1  E3 ubiquitin-protein ligase RNF38 isoform X3

      Conserved Domains (1) summary
      cd16472
      Location:538582
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    7. XM_006538300.5XP_006538363.1  E3 ubiquitin-protein ligase RNF38 isoform X5

      Conserved Domains (1) summary
      cd16472
      Location:430474
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    8. XM_036164491.1XP_036020384.1  E3 ubiquitin-protein ligase RNF38 isoform X7

      Conserved Domains (1) summary
      cd16472
      Location:377421
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    9. XM_006538305.4XP_006538368.1  E3 ubiquitin-protein ligase RNF38 isoform X7

      See identical proteins and their annotated locations for XP_006538368.1

      UniProtKB/TrEMBL
      Q3UH35
      Conserved Domains (1) summary
      cd16472
      Location:377421
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
    10. XM_006538301.4XP_006538364.1  E3 ubiquitin-protein ligase RNF38 isoform X6

      Conserved Domains (1) summary
      cd16472
      Location:425469
      RING-H2_RNF38_like; RING finger, H2 subclass, found in RING finger proteins RNF38, RNF44, and similar proteins
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