Format

Send to:

Choose Destination
    • Showing Current items.

    Gpbp1 GC-rich promoter binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 73274, updated on 31-Jan-2019

    Summary

    Official Symbol
    Gpbp1provided by MGI
    Official Full Name
    GC-rich promoter binding protein 1provided by MGI
    Primary source
    MGI:MGI:1920524
    See related
    Ensembl:ENSMUSG00000032745
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gpbp; mGPBP; AU019836; 1700034P14Rik; D230035M11Rik
    Expression
    Broad expression in placenta adult (RPKM 28.7), CNS E11.5 (RPKM 24.3) and 15 other tissues See more
    Orthologs

    Genomic context

    See Gpbp1 in Genome Data Viewer
    Location:
    13; 13 D2.2
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (111425680..111490125, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (112215888..112280249, complement)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene actin, beta-like 2 Neighboring gene electron transfer flavoprotein subunit alpha, mitochondrial pseudogene Neighboring gene predicted gene 15290 Neighboring gene predicted gene 15286

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription, DNA-templated IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001122963.2NP_001116435.1  vasculin isoform 1

      See identical proteins and their annotated locations for NP_001116435.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) lacks an alternate in-frame exon compared to variant 2. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 2.
      Source sequence(s)
      AC118475, AK145318
      Consensus CDS
      CCDS49362.1
      UniProtKB/Swiss-Prot
      Q6NXH3
      Related
      ENSMUSP00000088777.4, ENSMUST00000091236.10
      Conserved Domains (1) summary
      pfam15337
      Location:377457
      Vasculin; Vascular protein family Vasculin-like 1
    2. NM_001361923.1NP_001348852.1  vasculin isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate internal exon compared to variant 2. The resulting isoform (3) has a shorter and distinct N-terminus compared to isoform 2.
      Source sequence(s)
      AC118475
      Conserved Domains (1) summary
      pfam15337
      Location:272351
      Vasculin; Vascular protein family Vasculin-like 1
    3. NM_001361924.1NP_001348853.1  vasculin isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks two alternate internal exons compared to variant 2. The resulting isoform (4) has a shorter and distinct N-terminus and lacks an alternate internal segment compared to isoform 2.
      Source sequence(s)
      AC118475
      Conserved Domains (1) summary
      pfam15337
      Location:252331
      Vasculin; Vascular protein family Vasculin-like 1
    4. NM_001361925.1NP_001348854.1  vasculin isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks an alternate internal exon compared to variant 2. The resulting isoform (5) is shorter at the N-terminus compared to isoform 2. Variants 5 and 6 both encode the same isoform (5).
      Source sequence(s)
      AC118475
      Conserved Domains (1) summary
      pfam15337
      Location:206285
      Vasculin; Vascular protein family Vasculin-like 1
    5. NM_001361926.1NP_001348855.1  vasculin isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) lacks two alternate internal exons compared to variant 2. The resulting isoform (5) is shorter at the N-terminus compared to isoform 2. Variants 5 and 6 both encode the same isoform (5).
      Source sequence(s)
      AC118475
      Conserved Domains (1) summary
      pfam15337
      Location:206285
      Vasculin; Vascular protein family Vasculin-like 1
    6. NM_028487.5NP_082763.3  vasculin isoform 2

      See identical proteins and their annotated locations for NP_082763.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (2).
      Source sequence(s)
      AC118475, AK163390
      Consensus CDS
      CCDS26769.1
      UniProtKB/Swiss-Prot
      Q6NXH3
      Related
      ENSMUSP00000048240.7, ENSMUST00000047627.13
      Conserved Domains (1) summary
      pfam15337
      Location:397477
      Vasculin; Vascular protein family Vasculin-like 1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      111425680..111490125 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017315614.1XP_017171103.1  vasculin isoform X4

      UniProtKB/Swiss-Prot
      Q6NXH3
      Conserved Domains (1) summary
      pfam15337
      Location:206285
      Vasculin; Vascular protein family Vasculin-like 1
    2. XM_017315613.1XP_017171102.1  vasculin isoform X4

      UniProtKB/Swiss-Prot
      Q6NXH3
      Conserved Domains (1) summary
      pfam15337
      Location:206285
      Vasculin; Vascular protein family Vasculin-like 1
    3. XM_006517775.3XP_006517838.1  vasculin isoform X3

      Conserved Domains (1) summary
      pfam15337
      Location:252331
      Vasculin; Vascular protein family Vasculin-like 1
    4. XM_006517773.3XP_006517836.1  vasculin isoform X2

      UniProtKB/Swiss-Prot
      Q6NXH3
      Conserved Domains (1) summary
      pfam15337
      Location:272351
      Vasculin; Vascular protein family Vasculin-like 1
    5. XM_006517772.1XP_006517835.1  vasculin isoform X1

      See identical proteins and their annotated locations for XP_006517835.1

      UniProtKB/Swiss-Prot
      Q6NXH3
      Conserved Domains (1) summary
      pfam15337
      Location:397477
      Vasculin; Vascular protein family Vasculin-like 1
    Support Center