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    Otud3 OTU domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 73162, updated on 23-Jun-2021

    Summary

    Official Symbol
    Otud3provided by MGI
    Official Full Name
    OTU domain containing 3provided by MGI
    Primary source
    MGI:MGI:1920412
    See related
    Ensembl:ENSMUSG00000041161
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    3110030K17Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 16.1), colon adult (RPKM 5.5) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Otud3 in Genome Data Viewer
    Location:
    4; 4 D3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (138618374..138641322, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (138891063..138914026, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (138451294..138469862, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 13030 Neighboring gene phospholipase A2, group IIE Neighboring gene predicted gene, 18097 Neighboring gene predicted gene, 33011

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables thiol-dependent deubiquitinase IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables thiol-dependent deubiquitinase ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of protein kinase B signaling ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in protein K11-linked deubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein K11-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in protein K11-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein K27-linked deubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein K27-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in protein K48-linked deubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein K48-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in protein K6-linked deubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein K6-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in protein K6-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein deubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein stabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein stabilization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    OTU domain-containing protein 3
    NP_001364018.1
    NP_001364019.1
    NP_001364020.1
    NP_082729.1
    XP_017175895.1
    XP_017175896.1
    XP_017175897.1
    XP_030109689.1
    XP_030109690.1
    XP_036020376.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001377089.1NP_001364018.1  OTU domain-containing protein 3 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AL929473
      Conserved Domains (1) summary
      cl19932
      Location:70182
      OTU; OTU-like cysteine protease
    2. NM_001377090.1NP_001364019.1  OTU domain-containing protein 3 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL929473
      Conserved Domains (1) summary
      PRK10811
      Location:178258
      rne; ribonuclease E; Reviewed
    3. NM_001377091.1NP_001364020.1  OTU domain-containing protein 3 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL929473
      Conserved Domains (1) summary
      PRK10811
      Location:86166
      rne; ribonuclease E; Reviewed
    4. NM_028453.2NP_082729.1  OTU domain-containing protein 3 isoform 2

      See identical proteins and their annotated locations for NP_082729.1

      Status: VALIDATED

      Source sequence(s)
      AL929473
      Consensus CDS
      CCDS51337.1
      UniProtKB/Swiss-Prot
      B1AZ99
      Related
      ENSMUSP00000095441.4, ENSMUST00000097830.4
      Conserved Domains (1) summary
      cl19932
      Location:70182
      OTU; OTU-like cysteine protease

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      138618374..138641322 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320408.3XP_017175897.1  OTU domain-containing protein 3 isoform X2

      Conserved Domains (1) summary
      PRK10811
      Location:174254
      rne; ribonuclease E; Reviewed
    2. XM_030253829.2XP_030109689.1  OTU domain-containing protein 3 isoform X2

      Conserved Domains (1) summary
      PRK10811
      Location:174254
      rne; ribonuclease E; Reviewed
    3. XM_017320406.3XP_017175895.1  OTU domain-containing protein 3 isoform X1

      Conserved Domains (1) summary
      PRK10811
      Location:225305
      rne; ribonuclease E; Reviewed
    4. XM_036164483.1XP_036020376.1  OTU domain-containing protein 3 isoform X3

      Conserved Domains (1) summary
      PRK10811
      Location:127207
      rne; ribonuclease E; Reviewed
    5. XM_030253830.2XP_030109690.1  OTU domain-containing protein 3 isoform X3

      Conserved Domains (1) summary
      PRK10811
      Location:127207
      rne; ribonuclease E; Reviewed
    6. XM_017320407.3XP_017175896.1  OTU domain-containing protein 3 isoform X1

      Conserved Domains (1) summary
      PRK10811
      Location:225305
      rne; ribonuclease E; Reviewed
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