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    Otud3 OTU domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 73162, updated on 27-Jan-2018

    Summary

    Official Symbol
    Otud3provided by MGI
    Official Full Name
    OTU domain containing 3provided by MGI
    Primary source
    MGI:MGI:1920412
    See related
    Ensembl:ENSMUSG00000041161 Vega:OTTMUSG00000009799
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    3110030K17Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 16.1), colon adult (RPKM 5.5) and 26 other tissues See more
    Orthologs

    Genomic context

    See Otud3 in Genome Data Viewer
    Location:
    4; 4 D3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (138891063..138914018, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (138451294..138469862, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene 13030 Neighboring gene phospholipase A2, group IIE Neighboring gene predicted gene, 18097 Neighboring gene predicted gene, 33011

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    thiol-dependent ubiquitin-specific protease activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    thiol-dependent ubiquitinyl hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    negative regulation of protein kinase B signaling ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein K11-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein K27-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein K48-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein K6-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein stabilization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    OTU domain-containing protein 3
    NP_082729.1
    XP_017175894.1
    XP_017175895.1
    XP_017175896.1
    XP_017175897.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028453.1NP_082729.1  OTU domain-containing protein 3

      See identical proteins and their annotated locations for NP_082729.1

      Status: VALIDATED

      Source sequence(s)
      AL929473
      Consensus CDS
      CCDS51337.1
      UniProtKB/Swiss-Prot
      B1AZ99
      Related
      ENSMUSP00000095441.3, OTTMUSP00000010365, ENSMUST00000097830.3, OTTMUST00000022716
      Conserved Domains (1) summary
      cl19932
      Location:70182
      OTU; OTU-like cysteine protease

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      138891063..138914018 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320405.1XP_017175894.1  OTU domain-containing protein 3 isoform X1

    2. XM_017320408.1XP_017175897.1  OTU domain-containing protein 3 isoform X3

    3. XM_017320406.1XP_017175895.1  OTU domain-containing protein 3 isoform X2

    4. XM_017320407.1XP_017175896.1  OTU domain-containing protein 3 isoform X2

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