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    Ccser2 coiled-coil serine rich 2 [ Mus musculus (house mouse) ]

    Gene ID: 72972, updated on 22-Aug-2021

    Summary

    Official Symbol
    Ccser2provided by MGI
    Official Full Name
    coiled-coil serine rich 2provided by MGI
    Primary source
    MGI:MGI:101859
    See related
    Ensembl:ENSMUSG00000058690
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gcap; Gcap14; Fam190b; AI035535; AW108503; 1700012P13Rik; 2900054P12Rik
    Expression
    Ubiquitous expression in heart adult (RPKM 16.1), kidney adult (RPKM 14.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ccser2 in Genome Data Viewer
    Location:
    14; 14 B
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (36596893..36690762, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (36874936..36968841, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (37688122..37781950, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene SET translocation pseudogene Neighboring gene predicted gene, 25204 Neighboring gene predicted gene, 53853 Neighboring gene leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 Neighboring gene retinal G protein coupled receptor Neighboring gene leucine-rich repeat, immunoglobulin-like and transmembrane domains 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in microtubule bundle formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within microtubule bundle formation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in microtubule cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    serine-rich coiled-coil domain-containing protein 2
    Names
    coiled-coil serine-rich protein 2
    granule cell antiserum positive 14
    granule cell antiserum positive protein 14
    protein FAM190B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347502.1NP_001334431.1  serine-rich coiled-coil domain-containing protein 2 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and shorter 3' UTR. The encoded protein (isoform 2) has a longer and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK147383, BC111465, BM214039
      Consensus CDS
      CCDS84113.1
      UniProtKB/Swiss-Prot
      Q3UHI0
    2. NM_001347503.1NP_001334432.1  serine-rich coiled-coil domain-containing protein 2 isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in an isoform (4) with a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC154655, AK147383, BM214039, CJ103616, CV556741
      Consensus CDS
      CCDS84112.1
      UniProtKB/Swiss-Prot
      Q3UHI0
      UniProtKB/TrEMBL
      S4R211
      Related
      ENSMUSP00000138453.2, ENSMUST00000182042.2
    3. NM_027045.1NP_081321.1  serine-rich coiled-coil domain-containing protein 2 isoform 1

      See identical proteins and their annotated locations for NP_081321.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AK147383, BB871809, BM214039, CV556741
      Consensus CDS
      CCDS26948.1
      UniProtKB/Swiss-Prot
      Q3UHI0
      Related
      ENSMUSP00000087478.4, ENSMUST00000090024.11
    4. NM_028407.4NP_082683.2  serine-rich coiled-coil domain-containing protein 2 isoform 2

      See identical proteins and their annotated locations for NP_082683.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses a different 5' UTR segment, uses a downstream start codon, and lacks a segment in the 3' coding region, compared to variant 1. These changes result in a frameshift. The encoded protein (isoform 2) has a shorter N-terminus and a distinct C-terminus when compared to isoform 1.
      Source sequence(s)
      AC154655, AC158525
      Consensus CDS
      CCDS26947.1
      UniProtKB/Swiss-Prot
      Q3UHI0
      UniProtKB/TrEMBL
      A0A0R4J2A7
      Related
      ENSMUSP00000138718.2, ENSMUST00000183038.8

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      36596893..36690762 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030248048.2XP_030103908.1  serine-rich coiled-coil domain-containing protein 2 isoform X2

      Related
      ENSMUSP00000068550.7, ENSMUST00000067700.13
    2. XM_006519606.5XP_006519669.1  serine-rich coiled-coil domain-containing protein 2 isoform X5

    3. XM_006519605.4XP_006519668.1  serine-rich coiled-coil domain-containing protein 2 isoform X4

    4. XM_011245208.4XP_011243510.1  serine-rich coiled-coil domain-containing protein 2 isoform X3

    5. XM_036158858.1XP_036014751.1  serine-rich coiled-coil domain-containing protein 2 isoform X1

    6. XM_036158860.1XP_036014753.1  serine-rich coiled-coil domain-containing protein 2 isoform X7

    7. XM_006519607.3XP_006519670.1  serine-rich coiled-coil domain-containing protein 2 isoform X9

    8. XM_036158861.1XP_036014754.1  serine-rich coiled-coil domain-containing protein 2 isoform X8

    9. XM_036158863.1XP_036014756.1  serine-rich coiled-coil domain-containing protein 2 isoform X10

    10. XM_036158862.1XP_036014755.1  serine-rich coiled-coil domain-containing protein 2 isoform X8

    11. XM_036158859.1XP_036014752.1  serine-rich coiled-coil domain-containing protein 2 isoform X6

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