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    Hpf1 histone PARylation factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 72612, updated on 31-Jan-2019

    Summary

    Official Symbol
    Hpf1provided by MGI
    Official Full Name
    histone PARylation factor 1provided by MGI
    Primary source
    MGI:MGI:1919862
    See related
    Ensembl:ENSMUSG00000038005
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C4orf27; 2700029M09Rik; C230006B22Rik
    Expression
    Broad expression in liver E14 (RPKM 10.8), CNS E11.5 (RPKM 10.1) and 22 other tissues See more
    Orthologs

    Genomic context

    See Hpf1 in Genome Data Viewer
    Location:
    8; 8 B3.1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (60890394..60907580)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (63369248..63386369)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene 45651 Neighboring gene STAM binding protein, pseudogene 1 Neighboring gene chloride channel, voltage-sensitive 3 Neighboring gene predicted gene, 18394 Neighboring gene RIKEN cDNA B230317F23 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    poly-ADP-D-ribose binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    cellular response to DNA damage stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to DNA damage stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    peptidyl-serine ADP-ribosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peptidyl-serine ADP-ribosylation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of protein ADP-ribosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of protein ADP-ribosylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone PARylation factor 1; UPF0609 protein C4orf27 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357270.1NP_001344199.1  histone PARylation factor 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC114920, AK150453, AK151754, BB776576, CJ075373
      Conserved Domains (1) summary
      pfam10228
      Location:1159
      DUF2228; Uncharacterized conserved protein (DUF2228)
    2. NM_001357271.1NP_001344200.1  histone PARylation factor 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC114920
      Conserved Domains (1) summary
      pfam10228
      Location:1159
      DUF2228; Uncharacterized conserved protein (DUF2228)
    3. NM_028299.2NP_082575.1  histone PARylation factor 1 isoform 1

      See identical proteins and their annotated locations for NP_082575.1

      Status: VALIDATED

      Source sequence(s)
      AC114920, AK150453, BB776576, CJ075373
      Consensus CDS
      CCDS52553.1
      UniProtKB/Swiss-Prot
      Q8CFE2
      Related
      ENSMUSP00000047235.8, ENSMUST00000037190.14
      Conserved Domains (1) summary
      pfam10228
      Location:79328
      DUF2228; uncharacterized conserved protein (DUF2228)

    RNA

    1. NR_151662.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC114920

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      60890394..60907580
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509510.3XP_006509573.1  UPF0609 protein C4orf27 homolog isoform X1

      Conserved Domains (1) summary
      pfam10228
      Location:79314
      DUF2228; uncharacterized conserved protein (DUF2228)
    2. XM_006509511.3XP_006509574.1  UPF0609 protein C4orf27 homolog isoform X2

      Conserved Domains (1) summary
      pfam10228
      Location:79338
      DUF2228; uncharacterized conserved protein (DUF2228)
    3. XM_006509512.3XP_006509575.1  UPF0609 protein C4orf27 homolog isoform X3

      Conserved Domains (1) summary
      pfam10228
      Location:79304
      DUF2228; uncharacterized conserved protein (DUF2228)
    4. XM_017312975.1XP_017168464.1  UPF0609 protein C4orf27 homolog isoform X4

    5. XM_017312976.1XP_017168465.1  UPF0609 protein C4orf27 homolog isoform X5

      Conserved Domains (1) summary
      pfam10228
      Location:1159
      DUF2228; Uncharacterized conserved protein (DUF2228)

    RNA

    1. XR_378914.3 RNA Sequence

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