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    Lin9 lin-9 DREAM MuvB core complex component [ Mus musculus (house mouse) ]

    Gene ID: 72568, updated on 23-Jun-2021

    Summary

    Official Symbol
    Lin9provided by MGI
    Official Full Name
    lin-9 DREAM MuvB core complex componentprovided by MGI
    Primary source
    MGI:MGI:1919818
    See related
    Ensembl:ENSMUSG00000058729
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TGS; Bara; TGS1; Lin-9; mLin-9; 2700022J23Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 4.0), placenta adult (RPKM 3.7) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Lin9 in Genome Data Viewer
    Location:
    1; 1 H4
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (180468715..180518252)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (180641150..180690687)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (182571465..182620818)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene poly (ADP-ribose) polymerase family, member 1 Neighboring gene microRNA 6904 Neighboring gene predicted gene, 53485 Neighboring gene Mix1 homeobox-like 1 (Xenopus laevis) Neighboring gene acyl-Coenzyme A binding domain containing 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in reproduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of transcription repressor complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein lin-9 homolog
    Names
    TUDOR gene similar 1 protein
    lin-9 homolog
    type I interferon receptor beta chain-associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001103182.2NP_001096652.2  protein lin-9 homolog

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.
      Source sequence(s)
      AC167020, BC069181, BC088992
      Consensus CDS
      CCDS48468.2
      UniProtKB/TrEMBL
      A0A0A6YVZ7
      Related
      ENSMUSP00000141331.2, ENSMUST00000192561.6
      Conserved Domains (1) summary
      pfam06584
      Location:143247
      DIRP; DIRP

    RNA

    1. NR_120498.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site at an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC167020, BC088992
      Related
      ENSMUST00000193892.6

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      180468715..180518252
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496988.3XP_006497051.1  protein lin-9 homolog isoform X1

      See identical proteins and their annotated locations for XP_006497051.1

      Conserved Domains (1) summary
      pfam06584
      Location:75179
      DIRP
    2. XM_006496987.1XP_006497050.1  protein lin-9 homolog isoform X1

      See identical proteins and their annotated locations for XP_006497050.1

      Conserved Domains (1) summary
      pfam06584
      Location:75179
      DIRP

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_175186.4: Suppressed sequence

      Description
      NM_175186.4: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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