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    Exosc6 exosome component 6 [ Mus musculus (house mouse) ]

    Gene ID: 72544, updated on 31-Jan-2019

    Summary

    Official Symbol
    Exosc6provided by MGI
    Official Full Name
    exosome component 6provided by MGI
    Primary source
    MGI:MGI:1919794
    See related
    Ensembl:ENSMUSG00000109941
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mtr3; C76919; 2610510N21Rik
    Orthologs

    Genomic context

    See Exosc6 in Genome Data Viewer
    Location:
    8; 8 E1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (111056339..111057664)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (113580239..113581499)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b Neighboring gene microRNA 3473d Neighboring gene alanyl-tRNA synthetase Neighboring gene predicted gene, 38523 Neighboring gene nuclear encoded tRNA glycine 2 (anticodon GCC) Neighboring gene C-type lectin domain family 18, member A

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC151362

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    DNA deamination ISO
    Inferred from Sequence Orthology
    more info
     
    U4 snRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    isotype switching IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nuclear mRNA surveillance IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    polyadenylation-dependent snoRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of isotype switching IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    rRNA catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic exosome (RNase complex) IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    exosome (RNase complex) ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear exosome (RNase complex) IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    exosome complex component MTR3
    Names
    Mtr3 (mRNA transport regulator 3)-homolog
    exosome complex exonuclease MTR3
    NP_082550.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028274.4NP_082550.1  exosome complex component MTR3

      See identical proteins and their annotated locations for NP_082550.1

      Status: VALIDATED

      Source sequence(s)
      BC116985, BM941848
      Consensus CDS
      CCDS85611.1
      UniProtKB/Swiss-Prot
      Q8BTW3
      Related
      ENSMUSP00000147696.1, ENSMUST00000210390.1
      Conserved Domains (2) summary
      cd11371
      Location:36261
      RNase_PH_MTR3; MTR3 subunit of eukaryotic exosome
      COG0689
      Location:28260
      Rph; Ribonuclease PH [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      111056339..111057664
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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