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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_009206.1 RefSeqGene
- Range
-
5001..195778
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_523
mRNA and Protein(s)
-
NM_000369.5 → NP_000360.2 thyrotropin receptor isoform 1 precursor
See identical proteins and their annotated locations for NP_000360.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).
- Source sequence(s)
-
AC007262, AC010072, AL136040
- Consensus CDS
-
CCDS9872.1
- UniProtKB/TrEMBL
- A0A0A0MTJ0, Q59GA2
- Related
- ENSP00000298171.2, ENST00000298171.7
- Conserved Domains (4) summary
-
- sd00033
Location:54 → 77
- LRR_RI; leucine-rich repeat [structural motif]
- pfam00001
Location:431 → 678
- 7tm_1; 7 transmembrane receptor (rhodopsin family)
- pfam13306
Location:66 → 221
- LRR_5; Leucine rich repeats (6 copies)
- cl21561
Location:417 → 609
- 7tm_4; Olfactory receptor
-
NM_001018036.3 → NP_001018046.1 thyrotropin receptor isoform 2
See identical proteins and their annotated locations for NP_001018046.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2), also called ST4, differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
BC024205, BC063613
- Consensus CDS
-
CCDS32131.1
- UniProtKB/TrEMBL
-
Q0VAP8
- Related
- ENSP00000340113.6, ENST00000342443.10
- Conserved Domains (2) summary
-
- sd00033
Location:54 → 77
- LRR_RI; leucine-rich repeat [structural motif]
- pfam13306
Location:66 → 221
- LRR_5; Leucine rich repeats (6 copies)
-
NM_001142626.3 → NP_001136098.1 thyrotropin receptor isoform 3 precursor
See identical proteins and their annotated locations for NP_001136098.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence and uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus and contains an alternate internal segment compared to isoform 1.
- Source sequence(s)
-
BC024205, BC108653, BC127628
- Consensus CDS
-
CCDS55935.1
- UniProtKB/TrEMBL
-
Q0VAP8
- Related
- ENSP00000450549.1, ENST00000554435.1
- Conserved Domains (2) summary
-
- sd00033
Location:54 → 77
- LRR_RI; leucine-rich repeat [structural motif]
- pfam13306
Location:66 → 221
- LRR_5; Leucine rich repeats (6 copies)
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000014.9 Reference GRCh38.p14 Primary Assembly
- Range
-
80955621..81146306
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011537119.3 → XP_011535421.1 thyrotropin receptor isoform X1
- UniProtKB/TrEMBL
-
Q59GA2
- Conserved Domains (3) summary
-
- sd00033
Location:54 → 84
- LRR_RI; leucine-rich repeat [structural motif]
- pfam00001
Location:338 → 585
- 7tm_1; 7 transmembrane receptor (rhodopsin family)
- cl21561
Location:324 → 516
- 7tm_4; Olfactory receptor
Alternate T2T-CHM13v2.0
Genomic
-
NC_060938.1 Alternate T2T-CHM13v2.0
- Range
-
75167122..75358539
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054376675.1 → XP_054232650.1 thyrotropin receptor isoform X2
- UniProtKB/Swiss-Prot
- A0PJU7, F5GYU5, G3V2A9, P16473, Q16503, Q8TB90, Q96GT6, Q9P1V4, Q9ULA3, Q9UPH3
- UniProtKB/TrEMBL
-
Q59GA2
-
XM_054376677.1 → XP_054232652.1 thyrotropin receptor isoform X3
- UniProtKB/TrEMBL
-
Q0VAP8
-
XM_054376678.1 → XP_054232653.1 thyrotropin receptor isoform X4
- UniProtKB/TrEMBL
-
Q0VAP8
-
XM_054376676.1 → XP_054232651.1 thyrotropin receptor isoform X1
- UniProtKB/TrEMBL
-
Q59GA2