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    Wdr43 WD repeat domain 43 [ Mus musculus (house mouse) ]

    Gene ID: 72515, updated on 23-Jun-2021

    Summary

    Official Symbol
    Wdr43provided by MGI
    Official Full Name
    WD repeat domain 43provided by MGI
    Primary source
    MGI:MGI:1919765
    See related
    Ensembl:ENSMUSG00000041057
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Wrd43; AU020887; AV024208; mKIAA0007; 2610318G08Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 16.3), liver E14 (RPKM 11.3) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Wdr43 in Genome Data Viewer
    Location:
    17; 17 E1.3
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (71923175..71966026)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (71616178..71659031)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (71965555..72008371)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA cysteine 52 (anticodon GCA) Neighboring gene predicted gene, 30091 Neighboring gene small nucleolar RNA, C/D box 92 Neighboring gene small nucleolar RNA, C/D box 53 Neighboring gene predicted gene, 22858 Neighboring gene TOG array regulator of axonemal microtubules 2 Neighboring gene photoreceptor cilium actin regulator

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA polymerase II complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription elongation regulator activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    WD repeat-containing protein 43

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175639.1NP_783570.1  WD repeat-containing protein 43

      See identical proteins and their annotated locations for NP_783570.1

      Status: VALIDATED

      Source sequence(s)
      AK129031, AK152321, BY736005
      Consensus CDS
      CCDS50180.1
      UniProtKB/Swiss-Prot
      Q6ZQL4
      Related
      ENSMUSP00000048337.10, ENSMUST00000047086.10
      Conserved Domains (4) summary
      COG2319
      Location:19217
      WD40; WD40 repeat [General function prediction only]
      pfam04003
      Location:472568
      Utp12; Dip2/Utp12 Family
      sd00039
      Location:1957
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:19271
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      71923175..71966026
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_004939584.1 RNA Sequence

    2. XR_385368.5 RNA Sequence

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