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    Slc16a10 solute carrier family 16 (monocarboxylic acid transporters), member 10 [ Mus musculus (house mouse) ]

    Gene ID: 72472, updated on 28-Jun-2021

    Summary

    Official Symbol
    Slc16a10provided by MGI
    Official Full Name
    solute carrier family 16 (monocarboxylic acid transporters), member 10provided by MGI
    Primary source
    MGI:MGI:1919722
    See related
    Ensembl:ENSMUSG00000019838
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TAT; PRO0; TAT1; Mct10; PRO0813; 9830169E08; 2610103N14Rik
    Expression
    Broad expression in liver E14.5 (RPKM 16.2), genital fat pad adult (RPKM 15.9) and 22 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Slc16a10 in Genome Data Viewer
    Location:
    10; 10 B1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (39909528..40018262, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (40033532..40142270, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (39753341..39862060, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 4B3, pseudogene Neighboring gene major facilitator superfamily domain containing 4B5 Neighboring gene major facilitator superfamily domain containing 4B1 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 25613 Neighboring gene predicted gene, 31992 Neighboring gene ribosome production factor 2 homolog

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables aromatic amino acid transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables thyroid hormone transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in integral component of membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    monocarboxylate transporter 10
    Names
    MCT 10
    T-type amino acid transporter 1
    aromatic amino acid transporter 1
    solute carrier family 16 member 10

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114332.1NP_001107804.1  monocarboxylate transporter 10 isoform 1

      See identical proteins and their annotated locations for NP_001107804.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK151290, AK165240
      Consensus CDS
      CCDS48543.1
      UniProtKB/Swiss-Prot
      Q3U9N9
      Related
      ENSMUSP00000090227.7, ENSMUST00000092566.8
      Conserved Domains (2) summary
      cd06174
      Location:68467
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00892
      Location:53484
      2A0113; monocarboxylate transporter 1
    2. NM_028247.4NP_082523.1  monocarboxylate transporter 10 isoform 2

      See identical proteins and their annotated locations for NP_082523.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks several exons and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK165579
      Consensus CDS
      CCDS87990.1
      UniProtKB/Swiss-Prot
      Q3U9N9
      Related
      ENSMUSP00000150416.2, ENSMUST00000213488.2
      Conserved Domains (1) summary
      cd06174
      Location:68252
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      39909528..40018262 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512863.4XP_006512926.1  monocarboxylate transporter 10 isoform X1

      Conserved Domains (1) summary
      cl28910
      Location:1361
      MFS; Major Facilitator Superfamily

    RNA

    1. XR_380076.5 RNA Sequence

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