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    Htatsf1 HIV TAT specific factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 72459, updated on 26-Sep-2022

    Summary

    Official Symbol
    Htatsf1provided by MGI
    Official Full Name
    HIV TAT specific factor 1provided by MGI
    Primary source
    MGI:MGI:1919709
    See related
    Ensembl:ENSMUSG00000067873 AllianceGenome:MGI:1919709
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TAT-SF1; 1600023H17Rik; 2600017A12Rik; 2700077B20Rik
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be part of U2 snRNP and U2-type spliceosomal complex. Is expressed in brain; embryo; limb; limb mesenchyme; and nervous system. Orthologous to human HTATSF1 (HIV-1 Tat specific factor 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 27.5), placenta adult (RPKM 19.4) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Htatsf1 in Genome Data Viewer
    Location:
    X; X A6
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (56098930..56112543)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (57053570..57067183)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor G4 Neighboring gene bombesin-like receptor 3 Neighboring gene vestigial like family member 1 Neighboring gene predicted gene 14718

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of U2-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    HIV Tat-specific factor 1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028242.2NP_082518.1  HIV Tat-specific factor 1 homolog

      See identical proteins and their annotated locations for NP_082518.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AL672263
      Consensus CDS
      CCDS40983.1
      UniProtKB/Swiss-Prot
      Q8BGC0, Q9DAU3
      Related
      ENSMUSP00000086027.6, ENSMUST00000088652.6
      Conserved Domains (3) summary
      COG0724
      Location:89219
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12281
      Location:133223
      RRM1_TatSF1_like; RNA recognition motif 1 in HIV Tat-specific factor 1 (Tat-SF1) and similar proteins
      cd12282
      Location:264354
      RRM2_TatSF1_like; RNA recognition motif 2 in HIV Tat-specific factor 1 (Tat-SF1) and similar proteins
    2. NM_029371.1NP_083647.1  HIV Tat-specific factor 1 homolog

      See identical proteins and their annotated locations for NP_083647.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AI849205, AK049495, BG077525, BY134418
      Consensus CDS
      CCDS40983.1
      UniProtKB/Swiss-Prot
      Q8BGC0, Q9DAU3
      Conserved Domains (3) summary
      COG0724
      Location:89219
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12281
      Location:133223
      RRM1_TatSF1_like; RNA recognition motif 1 in HIV Tat-specific factor 1 (Tat-SF1) and similar proteins
      cd12282
      Location:264354
      RRM2_TatSF1_like; RNA recognition motif 2 in HIV Tat-specific factor 1 (Tat-SF1) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      56098930..56112543
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)