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    Rab38 RAB38, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 72433, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rab38provided by MGI
    Official Full Name
    RAB38, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:1919683
    See related
    Ensembl:ENSMUSG00000030559
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    cht; AU043391; 2310011F14Rik
    Expression
    Broad expression in limb E14.5 (RPKM 5.1), kidney adult (RPKM 3.0) and 18 other tissues See more
    Orthologs
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    Genomic context

    See Rab38 in Genome Data Viewer
    Location:
    7 D3; 7 49.19 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (88079481..88140780)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (88430273..88491572)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (95578783..95640082)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 25345 Neighboring gene predicted gene 2407 Neighboring gene ribosomal protein S13, pseudogene 2 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Spontaneous (1) 
    • Targeted (2)  1 citation
    • Chemically induced (ENU) (1) 
    • Endonuclease-mediated (5)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC107581

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables AP-1 adaptor complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables AP-3 adaptor complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables BLOC-2 complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in endosome to melanosome transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in melanosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in melanosome organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitochondrion organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phagosome acidification ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in platelet dense granule organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of phosphatidylcholine biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to membrane ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    colocalizes_with Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in melanosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in melanosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in melanosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in melanosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondria-associated endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in phagocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ras-related protein Rab-38
    Names
    RAB38, member of RAS oncogene family
    chocolate

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028238.7NP_082514.4  ras-related protein Rab-38

      See identical proteins and their annotated locations for NP_082514.4

      Status: VALIDATED

      Source sequence(s)
      AK054253
      Consensus CDS
      CCDS21439.1
      UniProtKB/Swiss-Prot
      Q8QZZ8
      UniProtKB/TrEMBL
      Q5FW76
      Related
      ENSMUSP00000102877.3, ENSMUST00000107256.4
      Conserved Domains (2) summary
      smart00175
      Location:10180
      RAB; Rab subfamily of small GTPases
      cd04107
      Location:10208
      Rab32_Rab38; Rab GTPase families 18 (Rab18) and 32 (Rab32)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      88079481..88140780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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