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    Sgo1 shugoshin 1 [ Mus musculus (house mouse) ]

    Gene ID: 72415, updated on 28-Aug-2021

    Summary

    Official Symbol
    Sgo1provided by MGI
    Official Full Name
    shugoshin 1provided by MGI
    Primary source
    MGI:MGI:1919665
    See related
    Ensembl:ENSMUSG00000023940
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sg; Sgol1; C81037; 3300001M08Rik
    Expression
    Biased expression in liver E14 (RPKM 10.7), CNS E11.5 (RPKM 8.5) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Sgo1 in Genome Data Viewer
    Location:
    17; 17 C
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (53981814..53996432, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (53674786..53691331, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (53814112..53828640, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene RAB5A, member RAS oncogene family Neighboring gene protein phosphatase 2C-like domain containing 1 Neighboring gene K(lysine) acetyltransferase 2B Neighboring gene 60S ribosomal protein L21 pseudogene Neighboring gene predicted gene, 31532 Neighboring gene RAB5A, member RAS oncogene family, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC113769

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables kinase binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in condensed chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in condensed chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    located_in kinetochore ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in spindle pole ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    shugoshin 1
    Names
    shugoshin 1A protein
    shugoshin-like 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028232.2NP_082508.1  shugoshin 1

      See identical proteins and their annotated locations for NP_082508.1

      Status: VALIDATED

      Source sequence(s)
      AK014357, AK049517, BY394301, CR522550
      Consensus CDS
      CCDS28881.1
      UniProtKB/Swiss-Prot
      Q9CXH7
      Related
      ENSMUSP00000024736.8, ENSMUST00000024736.14
      Conserved Domains (2) summary
      pfam07557
      Location:465486
      Shugoshin_C; Shugoshin C-terminus
      pfam07558
      Location:2266
      Shugoshin_N; Shugoshin N-terminal coiled-coil region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      53981814..53996432 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011246642.4XP_011244944.1  shugoshin 1 isoform X1

      See identical proteins and their annotated locations for XP_011244944.1

      UniProtKB/Swiss-Prot
      Q9CXH7
      Conserved Domains (2) summary
      pfam07557
      Location:465486
      Shugoshin_C; Shugoshin C-terminus
      pfam07558
      Location:2266
      Shugoshin_N; Shugoshin N-terminal coiled-coil region
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