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    Ccpg1 cell cycle progression 1 [ Mus musculus (house mouse) ]

    Gene ID: 72278, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ccpg1provided by MGI
    Official Full Name
    cell cycle progression 1provided by MGI
    Primary source
    MGI:MGI:1196419
    See related
    Ensembl:ENSMUSG00000034563
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CPR8; AI426686; AI875170; D9Ertd392e; 1700030B06Rik; 1810073J13Rik; 9430028F23Rik
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 12.0), frontal lobe adult (RPKM 11.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ccpg1 in Genome Data Viewer
    Location:
    9 D; 9 40.08 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (72985429..73016340)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (72833358..72863807)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene dynein axonemal assembly factor 4 Neighboring gene cell cycle progression 1, opposite strand Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class B Neighboring gene RIKEN cDNA 2310009A05 gene Neighboring gene RAB27A, member RAS oncogene family

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of Rho guanyl-nucleotide exchange factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cell cycle progression protein 1
    Names
    cell cycle progression 8 protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114328.2NP_001107800.1  cell cycle progression protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001107800.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) lacks an alternate exon in the 5' coding region and includes a 3' terminal exon that extends past a splice site that is used in variant 6. It encodes isoform 1, which has a distinct C-terminus and is shorter, compared to isoform 6.
      Source sequence(s)
      AK032645, BC082602, CN721780
      Consensus CDS
      CCDS52855.1
      UniProtKB/Swiss-Prot
      Q640L3
      Related
      ENSMUSP00000122966.1, ENSMUST00000150826.8
      Conserved Domains (1) summary
      pfam10577
      Location:133218
      UPF0560; uncharacterized protein family UPF0560
    2. NM_001286544.1NP_001273473.1  cell cycle progression protein 1 isoform 3

      See identical proteins and their annotated locations for NP_001273473.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate exon in the 5' coding region, compared to variant 6. It encodes a shorter isoform (3), compared to isoform 6.
      Source sequence(s)
      BC043049, CN721780
      Consensus CDS
      CCDS72278.1
      UniProtKB/Swiss-Prot
      Q640L3
      Related
      ENSMUSP00000082458.4, ENSMUST00000085350.10
      Conserved Domains (1) summary
      pfam10577
      Location:133218
      UPF0560; uncharacterized protein family UPF0560
    3. NM_001286545.1NP_001273474.1  cell cycle progression protein 1 isoform 4

      See identical proteins and their annotated locations for NP_001273474.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alternate exon in the 5' coding region and uses an alternate 3' structure, compared to variant 6. It encodes isoform 4, which has a distinct C-terminus and is shorter, compared to isoform 6.
      Source sequence(s)
      AC158997, AK134675, BC037183, BC043049, CN721780
      Consensus CDS
      CCDS72277.1
      UniProtKB/Swiss-Prot
      Q640L3
      UniProtKB/TrEMBL
      D3Z7R9
      Related
      ENSMUSP00000116976.1, ENSMUST00000140675.7
      Conserved Domains (1) summary
      pfam10577
      Location:133218
      UPF0560; uncharacterized protein family UPF0560
    4. NM_001286546.1NP_001273475.1  cell cycle progression protein 1 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks an alternate exon in the 5' coding region, uses an alternate internal splice site and includes a 3' terminal exon that extends past a splice site that is used in variant 6. It encodes isoform 5, which has a distinct C-terminus and is shorter, compared to isoform 6.
      Source sequence(s)
      AK032645, BC082602, CN721780
      UniProtKB/Swiss-Prot
      Q640L3
      Conserved Domains (2) summary
      COG1196
      Location:186445
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15662
      Location:32116
      SPATA3; Spermatogenesis-associated protein 3 family
    5. NM_001359295.1NP_001346224.1  cell cycle progression protein 1 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) represents the longest transcript and encodes the longest isoform (6).
      Source sequence(s)
      AC158997, BC043049
      Conserved Domains (2) summary
      pfam07267
      Location:130242
      Nucleo_P87; Nucleopolyhedrovirus capsid protein P87
      cl25732
      Location:318577
      SMC_N; RecF/RecN/SMC N terminal domain
    6. NM_001359296.1NP_001346225.1  cell cycle progression protein 1 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 6. It encodes isoform 7, which has a distinct C-terminus and is shorter, compared to isoform 6.
      Source sequence(s)
      AC158997, BC043049
      Conserved Domains (2) summary
      pfam07267
      Location:130242
      Nucleo_P87; Nucleopolyhedrovirus capsid protein P87
      cl25732
      Location:318577
      SMC_N; RecF/RecN/SMC N terminal domain
    7. NM_028181.5NP_082457.3  cell cycle progression protein 1 isoform 2

      See identical proteins and their annotated locations for NP_082457.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon in the 5' coding region and uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 6. It encodes isoform 2, which has a distinct C-terminus and is shorter, compared to isoform 6.
      Source sequence(s)
      AK076325, AK134675, BC043049, CN721780
      Consensus CDS
      CCDS23334.1
      UniProtKB/Swiss-Prot
      Q640L3
      Related
      ENSMUSP00000045669.7, ENSMUST00000037977.14
      Conserved Domains (1) summary
      pfam10577
      Location:133218
      UPF0560; uncharacterized protein family UPF0560

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      72985429..73016340
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511469.3XP_006511532.1  cell cycle progression protein 1 isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:318577
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam07267
      Location:64242
      Nucleo_P87; Nucleopolyhedrovirus capsid protein P87
    2. XM_006511467.3XP_006511530.1  cell cycle progression protein 1 isoform X1

      Conserved Domains (2) summary
      pfam07267
      Location:130242
      Nucleo_P87; Nucleopolyhedrovirus capsid protein P87
      cl25732
      Location:318577
      SMC_N; RecF/RecN/SMC N terminal domain
    3. XM_006511471.3XP_006511534.1  cell cycle progression protein 1 isoform X3

      Conserved Domains (2) summary
      pfam07267
      Location:130242
      Nucleo_P87; Nucleopolyhedrovirus capsid protein P87
      cl25732
      Location:318577
      SMC_N; RecF/RecN/SMC N terminal domain
    4. XM_006511468.3XP_006511531.1  cell cycle progression protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006511531.1

      Conserved Domains (2) summary
      pfam07267
      Location:130242
      Nucleo_P87; Nucleopolyhedrovirus capsid protein P87
      cl25732
      Location:318577
      SMC_N; RecF/RecN/SMC N terminal domain

    RNA

    1. XR_379460.3 RNA Sequence

    2. XR_870768.2 RNA Sequence

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