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    Mms19 MMS19 cytosolic iron-sulfur assembly component [ Mus musculus (house mouse) ]

    Gene ID: 72199, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mms19provided by MGI
    Official Full Name
    MMS19 cytosolic iron-sulfur assembly componentprovided by MGI
    Primary source
    MGI:MGI:1919449
    See related
    Ensembl:ENSMUSG00000025159
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mms1; C79368; C86341; Mms19l; AI316855; 2410001K24Rik; 2610042O15Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 24.9), ovary adult (RPKM 20.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Mms19 in Genome Data Viewer
    Location:
    19; 19 C3
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (41932146..41969603, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (41943707..41981164, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (42018197..42055626, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene phosphoglycerate mutase 1 Neighboring gene exosome component 1 Neighboring gene zinc finger, DHHC domain containing 16 Neighboring gene predicted gene, 23113 Neighboring gene ubiquitin domain containing 1 Neighboring gene ankyrin repeat domain 2 (stretch responsive muscle)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables enzyme binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables estrogen receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of CIA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of CIA complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of MMXD complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of MMXD complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    MMS19 nucleotide excision repair protein homolog
    Names
    MET18 homolog
    MMS19 (MET18 S. cerevisiae)
    MMS19-like protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001373946.1NP_001360875.1  MMS19 nucleotide excision repair protein homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC140193
      Related
      ENSMUSP00000026168.3, ENSMUST00000026168.9
      Conserved Domains (2) summary
      pfam12460
      Location:527962
      MMS19_C; RNAPII transcription regulator C-terminal
      pfam14500
      Location:54312
      MMS19_N; Dos2-interacting transcription regulator of RNA-Pol-II
    2. NM_028152.3NP_082428.1  MMS19 nucleotide excision repair protein homolog isoform 1

      See identical proteins and their annotated locations for NP_082428.1

      Status: VALIDATED

      Source sequence(s)
      AC140193
      Consensus CDS
      CCDS29818.1
      UniProtKB/Swiss-Prot
      Q9D071
      Related
      ENSMUSP00000130900.2, ENSMUST00000171561.8
      Conserved Domains (2) summary
      pfam12460
      Location:528963
      MMS19_C; RNAPII transcription regulator C-terminal
      pfam14500
      Location:54312
      MMS19_N; Dos2-interacting transcription regulator of RNA-Pol-II

    RNA

    1. NR_164197.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC140193
      Related
      ENSMUST00000163398.8

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      41932146..41969603 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247350.3XP_011245652.1  MMS19 nucleotide excision repair protein homolog isoform X2

      Conserved Domains (2) summary
      pfam12460
      Location:374809
      MMS19_C; RNAPII transcription regulator C-terminal
      pfam14500
      Location:26158
      MMS19_N; Dos2-interacting transcription regulator of RNA-Pol-II
    2. XM_030251078.2XP_030106938.1  MMS19 nucleotide excision repair protein homolog isoform X5

      Conserved Domains (1) summary
      pfam12460
      Location:163598
      MMS19_C; RNAPII transcription regulator C-terminal
    3. XM_030251082.2XP_030106942.1  MMS19 nucleotide excision repair protein homolog isoform X6

      Conserved Domains (1) summary
      pfam12460
      Location:162597
      MMS19_C; RNAPII transcription regulator C-terminal
    4. XM_030251081.2XP_030106941.1  MMS19 nucleotide excision repair protein homolog isoform X5

      Conserved Domains (1) summary
      pfam12460
      Location:163598
      MMS19_C; RNAPII transcription regulator C-terminal
    5. XM_030251080.1XP_030106940.1  MMS19 nucleotide excision repair protein homolog isoform X5

      Conserved Domains (1) summary
      pfam12460
      Location:163598
      MMS19_C; RNAPII transcription regulator C-terminal
    6. XM_030251079.1XP_030106939.1  MMS19 nucleotide excision repair protein homolog isoform X5

      Conserved Domains (1) summary
      pfam12460
      Location:163598
      MMS19_C; RNAPII transcription regulator C-terminal
    7. XM_011247349.4XP_011245651.1  MMS19 nucleotide excision repair protein homolog isoform X1

      See identical proteins and their annotated locations for XP_011245651.1

      Related
      ENSMUST00000171755.8
      Conserved Domains (2) summary
      pfam12460
      Location:528886
      MMS19_C; RNAPII transcription regulator C-terminal
      pfam14500
      Location:54312
      MMS19_N; Dos2-interacting transcription regulator of RNA-Pol-II
    8. XM_011247348.4XP_011245650.1  MMS19 nucleotide excision repair protein homolog isoform X1

      See identical proteins and their annotated locations for XP_011245650.1

      Conserved Domains (2) summary
      pfam12460
      Location:528886
      MMS19_C; RNAPII transcription regulator C-terminal
      pfam14500
      Location:54312
      MMS19_N; Dos2-interacting transcription regulator of RNA-Pol-II
    9. XM_017318292.3XP_017173781.1  MMS19 nucleotide excision repair protein homolog isoform X4

      Conserved Domains (2) summary
      pfam12460
      Location:527804
      MMS19_C; RNAPII transcription regulator C-terminal
      pfam14500
      Location:54312
      MMS19_N; Dos2-interacting transcription regulator of RNA-Pol-II
    10. XM_011247351.4XP_011245653.1  MMS19 nucleotide excision repair protein homolog isoform X3

      Conserved Domains (2) summary
      pfam12460
      Location:528805
      MMS19_C; RNAPII transcription regulator C-terminal
      pfam14500
      Location:54312
      MMS19_N; Dos2-interacting transcription regulator of RNA-Pol-II

    RNA

    1. XR_001782617.3 RNA Sequence

    2. XR_001782619.3 RNA Sequence

    3. XR_001782618.3 RNA Sequence

      Related
      ENSMUST00000164776.8
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