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    Rfc5 replication factor C (activator 1) 5 [ Mus musculus (house mouse) ]

    Gene ID: 72151, updated on 31-Jan-2019

    Summary

    Official Symbol
    Rfc5provided by MGI
    Official Full Name
    replication factor C (activator 1) 5provided by MGI
    Primary source
    MGI:MGI:1919401
    See related
    Ensembl:ENSMUSG00000029363
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    36kDa; Recc5; 36.5kDa; 2610020K06Rik; 2610209F07Rik
    Expression
    Ubiquitous expression in liver E14 (RPKM 17.2), liver E14.5 (RPKM 16.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Rfc5 in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (117379145..117389023, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (117829154..117839032, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102632031 Neighboring gene predicted gene, 42012 Neighboring gene WD repeat and SOCS box-containing 2 Neighboring gene kinase suppressor of ras 2 Neighboring gene predicted gene, 42013 Neighboring gene nitric oxide synthase 1, neuronal Neighboring gene predicted gene, 30360

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC113787

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to DNA clamp loader activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to DNA clamp loader activity ISO
    Inferred from Sequence Orthology
    more info
     
    enzyme binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to single-stranded DNA-dependent ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-dependent DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of DNA-directed DNA polymerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Ctf18 RFC-like complex ISO
    Inferred from Sequence Orthology
    more info
     
    DNA replication factor C complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA replication factor C complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    replication factor C subunit 5
    Names
    A1 36 kDa subunit
    RF-C 36 kDa subunit
    RFC36
    activator 1 36 kDa subunit
    activator 1 subunit 5
    replication factor C 36 kDa subunit
    replication factor C 5
    replication factor C, 36 kDa

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028128.1NP_082404.1  replication factor C subunit 5

      See identical proteins and their annotated locations for NP_082404.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089001
      Consensus CDS
      CCDS39235.1
      UniProtKB/Swiss-Prot
      Q9D0F6
      UniProtKB/TrEMBL
      Q5HZI8
      Related
      ENSMUSP00000083652.6, ENSMUST00000086461.12
      Conserved Domains (4) summary
      cd00009
      Location:34175
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      PRK00440
      Location:17328
      rfc; replication factor C small subunit; Reviewed
      pfam08542
      Location:257326
      Rep_fac_C; Replication factor C C-terminal domain
      pfam16193
      Location:191219
      AAA_assoc_2; AAA C-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      117379145..117389023 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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