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    Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit [ Mus musculus (house mouse) ]

    Gene ID: 72117, updated on 23-Jun-2021

    Summary

    Official Symbol
    Naa50provided by MGI
    Official Full Name
    N(alpha)-acetyltransferase 50, NatE catalytic subunitprovided by MGI
    Primary source
    MGI:MGI:1919367
    See related
    Ensembl:ENSMUSG00000022698
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Na; Mak; Nat; San; Mak3; Nat5; Mak3p; Nat13; AW112078; 2600005K24Rik; 2810441M03Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 17.1), liver E14 (RPKM 15.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Naa50 in Genome Data Viewer
    Location:
    16; 16 B4
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (43960154..43983825)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (44139791..44163462)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (44139922..44163477)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene GRAM domain containing 1C Neighboring gene microRNA 3470b Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit A Neighboring gene upstream transcription factor family member 3 Neighboring gene SID1 transmembrane family, member 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables H4 histone acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptide alpha-N-acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables peptidyl-lysine acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in N-terminal protein amino acid acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in N-terminal protein amino acid acetylation TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in establishment of mitotic sister chromatid cohesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitotic sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitotic sister chromatid cohesion, centromeric ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of NatA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of NatA complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    N-alpha-acetyltransferase 50
    Names
    Mak3 homolog
    Mak3p homolog
    N-acetyltransferase 13
    N-acetyltransferase NAT13
    N-epsilon-acetyltransferase 50
    Nalpha acetyltransferase 50
    natE catalytic subunit
    NP_001334168.1
    NP_082384.1
    XP_036016025.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347239.1NP_001334168.1  N-alpha-acetyltransferase 50 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC125098, AK167141, AK168394, BC057117, BF020411
      Consensus CDS
      CCDS84236.1
      UniProtKB/Swiss-Prot
      Q6PGB6
      Related
      ENSMUSP00000124291.2, ENSMUST00000161326.8
      Conserved Domains (1) summary
      COG0456
      Location:10145
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
    2. NM_028108.3NP_082384.1  N-alpha-acetyltransferase 50 isoform 1

      See identical proteins and their annotated locations for NP_082384.1

      Status: VALIDATED

      Source sequence(s)
      AC125098
      Consensus CDS
      CCDS28183.1
      UniProtKB/Swiss-Prot
      Q6PGB6
      Related
      ENSMUSP00000070140.9, ENSMUST00000063520.15
      Conserved Domains (1) summary
      COG0456
      Location:9144
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      43960154..43983825
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160132.1XP_036016025.1  N-alpha-acetyltransferase 50 isoform X1

      Related
      ENSMUSP00000125517.2, ENSMUST00000159514.8
      Conserved Domains (1) summary
      COG0456
      Location:16151
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
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