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    Cnn3 calponin 3, acidic [ Mus musculus (house mouse) ]

    Gene ID: 71994, updated on 19-Mar-2019

    Summary

    Official Symbol
    Cnn3provided by MGI
    Official Full Name
    calponin 3, acidicprovided by MGI
    Primary source
    MGI:MGI:1919244
    See related
    Ensembl:ENSMUSG00000053931
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C85854; Calpo3; 1600014M03Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 221.9), ovary adult (RPKM 202.5) and 27 other tissues See more
    Orthologs

    Genomic context

    See Cnn3 in Genome Data Viewer
    Location:
    3; 3 G1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (121426541..121458205)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (121129459..121161123)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 33363 Neighboring gene peptidylprolyl isomerase A pseudogene 3_1234.1 Neighboring gene predicted gene, 40134 Neighboring gene solute carrier family 44, member 3 Neighboring gene RIKEN cDNA A530020G20 gene Neighboring gene predicted gene, 38684

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    actomyosin structure organization IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic spine ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    calponin-3
    Names
    calponin, acidic isoform

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028044.2NP_082320.1  calponin-3

      See identical proteins and their annotated locations for NP_082320.1

      Status: PROVISIONAL

      Source sequence(s)
      AK005460
      Consensus CDS
      CCDS17802.1
      UniProtKB/Swiss-Prot
      Q9DAW9
      Related
      ENSMUSP00000029773.8, ENSMUST00000029773.12
      Conserved Domains (2) summary
      cd00014
      Location:28125
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam00402
      Location:164187
      Calponin; Calponin family repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      121426541..121458205
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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