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    Cnn3 calponin 3, acidic [ Mus musculus (house mouse) ]

    Gene ID: 71994, updated on 26-Sep-2022


    Official Symbol
    Cnn3provided by MGI
    Official Full Name
    calponin 3, acidicprovided by MGI
    Primary source
    See related
    Ensembl:ENSMUSG00000053931 AllianceGenome:MGI:1919244
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Calpo3; 1600014M03Rik
    Predicted to enable microtubule binding activity. Predicted to be involved in negative regulation of ATPase activity. Predicted to be located in several cellular components, including dendritic spine; neuronal cell body; and postsynaptic density. Predicted to be active in cytoskeleton. Is expressed in several structures, including body cavity or lining; genitourinary system; integumental system; respiratory system; and vertebral axis musculature. Orthologous to human CNN3 (calponin 3). [provided by Alliance of Genome Resources, Apr 2022]
    Ubiquitous expression in limb E14.5 (RPKM 221.9), ovary adult (RPKM 202.5) and 27 other tissues See more
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    Genomic context

    See Cnn3 in Genome Data Viewer
    3; 3 G1
    Exon count:
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (121220190..121251854)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (121426541..121458205)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33363 Neighboring gene peptidylprolyl isomerase A pseudogene 3_1234.1 Neighboring gene predicted gene, 40134 Neighboring gene solute carrier family 44, member 3 Neighboring gene RIKEN cDNA A530020G20 gene Neighboring gene predicted gene, 38684

    Genomic regions, transcripts, and products


    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a


    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?



    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2)  1 citation
    • Endonuclease-mediated (2) 


    Products Interactant Other Gene Complex Source Pubs Description

    General gene information



    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
    Process Evidence Code Pubs
    involved_in actomyosin structure organization IEA
    Inferred from Electronic Annotation
    more info
    involved_in negative regulation of ATP-dependent activity ISO
    Inferred from Sequence Orthology
    more info
    Component Evidence Code Pubs
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
    located_in dendritic spine ISO
    Inferred from Sequence Orthology
    more info
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
    located_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028044.2NP_082320.1  calponin-3

      See identical proteins and their annotated locations for NP_082320.1

      Status: PROVISIONAL

      Source sequence(s)
      Consensus CDS
      Q3TW23, Q9DAW9
      A0A6P5PK14, A0A8C6HHG8
      ENSMUSP00000029773.9, ENSMUST00000029773.13
      Conserved Domains (2) summary
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      Calponin; Calponin family repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000069.7 Reference GRCm39 C57BL/6J

      GenBank, FASTA, Sequence Viewer (Graphics)