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    Bdh1 3-hydroxybutyrate dehydrogenase, type 1 [ Mus musculus (house mouse) ]

    Gene ID: 71911, updated on 31-Jan-2019

    Summary

    Official Symbol
    Bdh1provided by MGI
    Official Full Name
    3-hydroxybutyrate dehydrogenase, type 1provided by MGI
    Primary source
    MGI:MGI:1919161
    See related
    Ensembl:ENSMUSG00000046598
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bdh; AI327223; 2310032J20Rik
    Expression
    Broad expression in liver adult (RPKM 77.8), liver E18 (RPKM 72.6) and 21 other tissues See more
    Orthologs

    Genomic context

    See Bdh1 in Genome Data Viewer
    Location:
    16; 16 B2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (31422297..31458901)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (31422383..31458987)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41443 Neighboring gene RIKEN cDNA 1700007E05 gene Neighboring gene predicted gene 15743 Neighboring gene predicted gene, 34032 Neighboring gene predicted gene, 46560 Neighboring gene predicted gene, 34256

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    3-hydroxybutyrate dehydrogenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phospholipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial inner membrane HDA PubMed 
    mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    D-beta-hydroxybutyrate dehydrogenase, mitochondrial
    Names
    3-hydroxybutyrate dehydrogenase (heart, mitochondrial)
    b-hydroxybutyrate dehydrogenase
    NP_001116155.1
    NP_780386.3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001122683.1NP_001116155.1  D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001116155.1

      Status: VALIDATED

      Source sequence(s)
      AA789526, AK145711, AK146962, BE979314
      Consensus CDS
      CCDS28106.1
      UniProtKB/Swiss-Prot
      Q80XN0
      Related
      ENSMUSP00000110882.3, ENSMUST00000115227.9
      Conserved Domains (2) summary
      cd09805
      Location:56341
      type2_17beta_HSD-like_SDR_c; human 17beta-hydroxysteroid dehydrogenase type 2 (type 2 17beta-HSD)-like, classical (c) SDRs
      pfam00106
      Location:56241
      adh_short; short chain dehydrogenase
    2. NM_175177.4NP_780386.3  D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor

      See identical proteins and their annotated locations for NP_780386.3

      Status: VALIDATED

      Source sequence(s)
      AA789526, AK145711, AK146962, BE979314, BY148101
      Consensus CDS
      CCDS28106.1
      UniProtKB/Swiss-Prot
      Q80XN0
      Related
      ENSMUSP00000087192.2, ENSMUST00000089759.8
      Conserved Domains (2) summary
      cd09805
      Location:56341
      type2_17beta_HSD-like_SDR_c; human 17beta-hydroxysteroid dehydrogenase type 2 (type 2 17beta-HSD)-like, classical (c) SDRs
      pfam00106
      Location:56241
      adh_short; short chain dehydrogenase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      31422297..31458901
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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