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    Cand1 cullin associated and neddylation disassociated 1 [ Mus musculus (house mouse) ]

    Gene ID: 71902, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cand1provided by MGI
    Official Full Name
    cullin associated and neddylation disassociated 1provided by MGI
    Primary source
    MGI:MGI:1261820
    See related
    Ensembl:ENSMUSG00000020114
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tp120a; AI195005; AI846556; mKIAA0829; D10Ertd516e; 2310038O07Rik; 6330512O03Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 13.0), placenta adult (RPKM 11.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cand1 in Genome Data Viewer
    Location:
    10 D2; 10 67.08 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (119198812..119240055, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (118635868..118677111, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 33982 Neighboring gene predicted gene, 34045 Neighboring gene RIKEN cDNA 4930477N07 gene Neighboring gene proteasome (prosome, macropain) subunit, alpha type 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    TBP-class protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    SCF complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    SCF complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of catalytic activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    cullin-RING ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cullin-associated NEDD8-dissociated protein 1
    Names
    TBP-interacting protein
    cullin-associated and neddylation-dissociated protein 1
    p120 CAND1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027994.1NP_082270.1  cullin-associated NEDD8-dissociated protein 1

      See identical proteins and their annotated locations for NP_082270.1

      Status: VALIDATED

      Source sequence(s)
      AC160063
      Consensus CDS
      CCDS48701.1
      UniProtKB/Swiss-Prot
      Q6ZQ38
      Related
      ENSMUSP00000020315.6, ENSMUST00000020315.12
      Conserved Domains (4) summary
      cd00020
      Location:650745
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam08623
      Location:10401202
      TIP120; TATA-binding protein interacting (TIP20)
      pfam13513
      Location:149202
      HEAT_EZ; HEAT-like repeat
      sd00044
      Location:817847
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      119198812..119240055 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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