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    Dcaf7 DDB1 and CUL4 associated factor 7 [ Mus musculus (house mouse) ]

    Gene ID: 71833, updated on 23-Jun-2021

    Summary

    Official Symbol
    Dcaf7provided by MGI
    Official Full Name
    DDB1 and CUL4 associated factor 7provided by MGI
    Primary source
    MGI:MGI:1919083
    See related
    Ensembl:ENSMUSG00000049354
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Wdr6; HAN11; Wdr68; C86529; 1700012F10Rik; 2610037L01Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 52.6), whole brain E14.5 (RPKM 48.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Dcaf7 in Genome Data Viewer
    Location:
    11; 11 E1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (105927698..105950150)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (106036872..106059324)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (105898186..105920638)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35971 Neighboring gene angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 Neighboring gene potassium voltage-gated channel, subfamily H (eag-related), member 6 Neighboring gene translational activator of mitochondrially encoded cytochrome c oxidase I, opposite strand Neighboring gene translational activator of mitochondrially encoded cytochrome c oxidase I Neighboring gene mitogen-activated protein kinase kinase kinase 3 Neighboring gene LIM domain containing 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    DDB1- and CUL4-associated factor 7
    Names
    WD repeat domain 68
    WD repeat-containing protein 68
    WD repeat-containing protein An11 homolog
    WD-repeat protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027946.3NP_082222.1  DDB1- and CUL4-associated factor 7

      See identical proteins and their annotated locations for NP_082222.1

      Status: VALIDATED

      Source sequence(s)
      AK047435, BB646282, BC048165
      Consensus CDS
      CCDS25546.1
      UniProtKB/Swiss-Prot
      P61963
      UniProtKB/TrEMBL
      Q80ZU1
      Related
      ENSMUSP00000058168.9, ENSMUST00000058438.9
      Conserved Domains (2) summary
      sd00039
      Location:71116
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:19295
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      105927698..105950150
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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