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    Kif23 kinesin family member 23 [ Mus musculus (house mouse) ]

    Gene ID: 71819, updated on 2-Oct-2018

    Summary

    Official Symbol
    Kif23provided by MGI
    Official Full Name
    kinesin family member 23provided by MGI
    Primary source
    MGI:MGI:1919069
    See related
    Ensembl:ENSMUSG00000032254 Vega:OTTMUSG00000062532
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CHO1; Knsl5; MKLP1; C87313; MKLP-1; 3110001D19Rik
    Expression
    Biased expression in CNS E11.5 (RPKM 14.9), liver E14 (RPKM 11.3) and 13 other tissues See more
    Orthologs

    Genomic context

    See Kif23 in Genome Data Viewer
    Location:
    9; 9 B
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (61917277..61946813, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (61765084..61794606, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 35058 Neighboring gene ribosomal protein, large, P1 Neighboring gene progestin and adipoQ receptor family member V Neighboring gene predicted gene, 35152 Neighboring gene glucuronyl C5-epimerase Neighboring gene microRNA 5133

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    actomyosin contractile ring assembly IEA
    Inferred from Electronic Annotation
    more info
     
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle midzone assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic spindle midzone assembly ISO
    Inferred from Sequence Orthology
    more info
     
    plus-end-directed vesicle transport along microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    centralspindlin complex ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    intercellular bridge IDA
    Inferred from Direct Assay
    more info
    PubMed 
    kinesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    midbody ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    spindle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    kinesin-like protein KIF23
    Names
    kinesin-like 5 (mitotic kinesin-like protein 1)

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024245.4NP_077207.3  kinesin-like protein KIF23

      See identical proteins and their annotated locations for NP_077207.3

      Status: VALIDATED

      Source sequence(s)
      AC151969, AI132370, AK030771, BB688982, BY132148
      Consensus CDS
      CCDS40662.1
      UniProtKB/Swiss-Prot
      E9Q5G3
      Related
      ENSMUSP00000034815.7, OTTMUSP00000078973, ENSMUST00000034815.8, OTTMUST00000152329
      Conserved Domains (4) summary
      cd01368
      Location:24434
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
      pfam00225
      Location:31436
      Kinesin; Kinesin motor domain
      pfam08702
      Location:498603
      Fib_alpha; Fibrinogen alpha/beta chain family
      pfam16540
      Location:797896
      MKLP1_Arf_bdg; Arf6-interacting domain of mitotic kinesin-like protein 1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      61917277..61946813 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511453.3XP_006511516.1  kinesin-like protein KIF23 isoform X2

      Conserved Domains (4) summary
      cd01368
      Location:24448
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
      pfam00225
      Location:31450
      Kinesin; Kinesin motor domain
      pfam08702
      Location:512617
      Fib_alpha; Fibrinogen alpha/beta chain family
      pfam16540
      Location:811910
      MKLP1_Arf_bdg; Arf6-interacting domain of mitotic kinesin-like protein 1
    2. XM_006511452.3XP_006511515.1  kinesin-like protein KIF23 isoform X1

      Conserved Domains (4) summary
      cd01368
      Location:24448
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
      pfam00225
      Location:31450
      Kinesin; Kinesin motor domain
      pfam08702
      Location:512617
      Fib_alpha; Fibrinogen alpha/beta chain family
      pfam16540
      Location:811910
      MKLP1_Arf_bdg; Arf6-interacting domain of mitotic kinesin-like protein 1
    3. XM_006511454.3XP_006511517.1  kinesin-like protein KIF23 isoform X3

      Conserved Domains (4) summary
      cd01368
      Location:24448
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
      pfam00225
      Location:31450
      Kinesin; Kinesin motor domain
      pfam08702
      Location:512617
      Fib_alpha; Fibrinogen alpha/beta chain family
      pfam16540
      Location:707806
      MKLP1_Arf_bdg; Arf6-interacting domain of mitotic kinesin-like protein 1
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