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    Ranbp3 RAN binding protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 71810, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ranbp3provided by MGI
    Official Full Name
    RAN binding protein 3provided by MGI
    Primary source
    MGI:MGI:1919060
    See related
    Ensembl:ENSMUSG00000002372
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AA408221; 2610024N24Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 37.4), ovary adult (RPKM 34.4) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ranbp3 in Genome Data Viewer
    Location:
    17; 17 D
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (56980225..57018769)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (56673225..56711769)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (56812680..56851192)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene lon peptidase 1, mitochondrial Neighboring gene cation channel sperm associated auxiliary subunit delta Neighboring gene predicted gene, 33461 Neighboring gene calcyphosine, pseudogene Neighboring gene NADH:ubiquinone oxidoreductase subunit A11 Neighboring gene vimentin-type intermediate filament associated coiled-coil protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables R-SMAD binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001252466.1NP_001239395.1  ran-binding protein 3 isoform 1

      See identical proteins and their annotated locations for NP_001239395.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      BB726920, BC066005, CA318306, CT010491
      Consensus CDS
      CCDS89127.1
      Related
      ENSMUSP00000156588.2, ENSMUST00000233319.2
      Conserved Domains (1) summary
      cd13180
      Location:384499
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
    2. NM_001252467.1NP_001239396.1  ran-binding protein 3 isoform 3

      See identical proteins and their annotated locations for NP_001239396.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks three exons in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
      Source sequence(s)
      BB726920, BC066005, CN717165, CT010491
      Conserved Domains (1) summary
      cd13180
      Location:264379
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
    3. NM_027933.3NP_082209.1  ran-binding protein 3 isoform 2

      See identical proteins and their annotated locations for NP_082209.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an exon in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AK133949, BB726920, CT010491
      Consensus CDS
      CCDS28911.1
      UniProtKB/Swiss-Prot
      Q9CT10
      Related
      ENSMUSP00000002445.9, ENSMUST00000002445.10
      Conserved Domains (1) summary
      cd13180
      Location:317432
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain

    RNA

    1. NR_045519.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an internal exon and includes an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      BB726920, BC066005, BM950080, CT010491

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      56980225..57018769
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524945.4XP_006525008.1  ran-binding protein 3 isoform X6

      Conserved Domains (1) summary
      cd13180
      Location:353468
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
    2. XM_030250054.1XP_030105914.1  ran-binding protein 3 isoform X8

      Conserved Domains (1) summary
      cd13180
      Location:331446
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
    3. XM_030250055.1XP_030105915.1  ran-binding protein 3 isoform X10

      Conserved Domains (1) summary
      cd13180
      Location:286401
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
    4. XM_006524944.2XP_006525007.1  ran-binding protein 3 isoform X1

      Conserved Domains (1) summary
      cd13180
      Location:437552
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
    5. XM_017317645.3XP_017173134.1  ran-binding protein 3 isoform X3

      Conserved Domains (1) summary
      cd13180
      Location:406521
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
    6. XM_017317646.2XP_017173135.1  ran-binding protein 3 isoform X4

      Conserved Domains (1) summary
      cd13180
      Location:384499
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
    7. XM_017317647.1XP_017173136.1  ran-binding protein 3 isoform X5

      Conserved Domains (1) summary
      cd13180
      Location:370485
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
    8. XM_017317648.1XP_017173137.1  ran-binding protein 3 isoform X7

      Conserved Domains (2) summary
      cd13180
      Location:339454
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
      pfam15392
      Location:4204
      Joubert; Joubert syndrome-associated
    9. XM_017317649.1XP_017173138.1  ran-binding protein 3 isoform X9

      Conserved Domains (1) summary
      cd13180
      Location:317432
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
    10. XM_011246620.1XP_011244922.1  ran-binding protein 3 isoform X2

      Conserved Domains (1) summary
      cd13180
      Location:410525
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain
    11. XM_030250056.1XP_030105916.1  ran-binding protein 3 isoform X11

      Conserved Domains (1) summary
      cd13180
      Location:192307
      RanBD_RanBP3; Ran-binding protein 3 Ran-binding domain

    RNA

    1. XR_004939581.1 RNA Sequence

    2. XR_001782113.3 RNA Sequence

    3. XR_004939580.1 RNA Sequence

    4. XR_003952184.2 RNA Sequence

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