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    Nup93 nucleoporin 93 [ Mus musculus (house mouse) ]

    Gene ID: 71805, updated on 5-Aug-2018

    Summary

    Official Symbol
    Nup93provided by MGI
    Official Full Name
    nucleoporin 93provided by MGI
    Primary source
    MGI:MGI:1919055
    See related
    Ensembl:ENSMUSG00000032939 Vega:OTTMUSG00000061621
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2410008G02Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 18.5), limb E14.5 (RPKM 14.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Nup93 in Genome Data Viewer
    Location:
    8; 8 C5
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (94214540..94315066)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (96738501..96838966)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 39228 Neighboring gene metallothionein 1 Neighboring gene ribosomal protein L10, pseudogene 5 Neighboring gene microRNA 138-2 Neighboring gene solute carrier family 12, member 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    structural constituent of nuclear pore ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    SMAD protein signal transduction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    SMAD protein signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    glomerular visceral epithelial cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glomerular visceral epithelial cell development ISO
    Inferred from Sequence Orthology
    more info
     
    glomerular visceral epithelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of hydrogen peroxide-induced cell death ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear envelope organization ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear pore complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear pore complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    poly(A)+ mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of SMAD protein signal transduction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of SMAD protein signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    renal system development ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear periphery ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear pore ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nuclear pore complex protein Nup93
    Names
    93 kDa nucleoporin
    CBP-interacting protein 4
    nucleoporin Nup93

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357266.1NP_001344195.1  nuclear pore complex protein Nup93 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC131733, AK028864, AK167105
      Conserved Domains (1) summary
      pfam04097
      Location:220802
      Nic96; Nup93/Nic96
    2. NM_001357267.1NP_001344196.1  nuclear pore complex protein Nup93 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC128663, AC131733
      Conserved Domains (1) summary
      pfam04097
      Location:97679
      Nic96; Nup93/Nic96
    3. NM_001357268.1NP_001344197.1  nuclear pore complex protein Nup93 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC128663, AK045380
      Conserved Domains (1) summary
      pfam04097
      Location:97679
      Nic96; Nup93/Nic96
    4. NM_172410.3NP_765998.1  nuclear pore complex protein Nup93 isoform 1

      See identical proteins and their annotated locations for NP_765998.1

      Status: VALIDATED

      Source sequence(s)
      AC131733, AK028864
      Consensus CDS
      CCDS22540.1
      UniProtKB/Swiss-Prot
      Q8BJ71
      Related
      ENSMUSP00000148700.1, OTTMUSP00000077952, ENSMUST00000212824.1
      Conserved Domains (1) summary
      pfam04097
      Location:220802
      Nic96; Nup93/Nic96

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      94214540..94315066
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531374.3XP_006531437.1  nuclear pore complex protein Nup93 isoform X1

      UniProtKB/Swiss-Prot
      Q8BJ71
      Related
      ENSMUSP00000078878.6, OTTMUSP00000077951, ENSMUST00000079961.13, OTTMUST00000150340
      Conserved Domains (1) summary
      pfam04097
      Location:220802
      Nic96; Nup93/Nic96
    2. XM_006531375.3XP_006531438.1  nuclear pore complex protein Nup93 isoform X2

      UniProtKB/Swiss-Prot
      Q8BJ71
      Conserved Domains (1) summary
      pfam04097
      Location:97679
      Nic96; Nup93/Nic96
    3. XM_006531376.2XP_006531439.1  nuclear pore complex protein Nup93 isoform X2

      See identical proteins and their annotated locations for XP_006531439.1

      UniProtKB/Swiss-Prot
      Q8BJ71
      Related
      ENSMUSP00000148458.1, OTTMUSP00000077954, ENSMUST00000211822.1, OTTMUST00000150345
      Conserved Domains (1) summary
      pfam04097
      Location:97679
      Nic96; Nup93/Nic96
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