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    Gtf3c2 general transcription factor IIIC, polypeptide 2, beta [ Mus musculus (house mouse) ]

    Gene ID: 71752, updated on 23-Jun-2021

    Summary

    Official Symbol
    Gtf3c2provided by MGI
    Official Full Name
    general transcription factor IIIC, polypeptide 2, betaprovided by MGI
    Primary source
    MGI:MGI:1919002
    See related
    Ensembl:ENSMUSG00000106864
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TFIIIC; TFIIIC-; AI225816; AU041069; TFIIIC110; mKIAA0011; 1300004C11Rik; 2610510G03Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 28.4), CNS E11.5 (RPKM 24.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Gtf3c2 in Genome Data Viewer
    Location:
    5; 5 B1
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (31313350..31337488, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (31156006..31180144, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (31458379..31482517, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene urocortin Neighboring gene MpV17 mitochondrial inner membrane protein Neighboring gene eukaryotic translation initiation factor 2B, subunit 4 delta Neighboring gene sorting nexin 17

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Potential readthrough

    Included gene: Mpv17

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in transcription by RNA polymerase III ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of transcription factor TFIIIC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of transcription factor TFIIIC complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    general transcription factor 3C polypeptide 2
    Names
    TF3C-beta
    TFIIIC 110 kDa subunit
    TFIIIC-BETA
    transcription factor IIIC 110 kDa subunit
    transcription factor IIIC subunit beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027901.2NP_082177.2  general transcription factor 3C polypeptide 2

      See identical proteins and their annotated locations for NP_082177.2

      Status: VALIDATED

      Source sequence(s)
      AK012095, AK083585, AK152439
      Consensus CDS
      CCDS39053.1
      UniProtKB/Swiss-Prot
      Q8BL74
      Related
      ENSMUSP00000085325.6, ENSMUST00000088010.12
      Conserved Domains (4) summary
      smart00527
      Location:166243
      HMG17; domain in high mobilty group proteins HMG14 and HMG 17
      COG2319
      Location:554719
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:554591
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:555640
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      31313350..31337488 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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