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    Cdc40 cell division cycle 40 [ Mus musculus (house mouse) ]

    Gene ID: 71713, updated on 22-Aug-2021

    Summary

    Official Symbol
    Cdc40provided by MGI
    Official Full Name
    cell division cycle 40provided by MGI
    Primary source
    MGI:MGI:1918963
    See related
    Ensembl:ENSMUSG00000038446
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PR; EHB3; PRP17; 1200003H23Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 9.4), placenta adult (RPKM 7.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Cdc40 in Genome Data Viewer
    Location:
    10; 10 B1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (40707617..40759139, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (40831621..40883143, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (40552699..40602949, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene D-aspartate oxidase Neighboring gene methyltransferase like 24 Neighboring gene WASP family, member 1 Neighboring gene predicted gene, 48057

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of U2-type catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    pre-mRNA-processing factor 17
    Names
    PRP17 homolog
    cell division cycle 40 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027879.2NP_082155.1  pre-mRNA-processing factor 17

      See identical proteins and their annotated locations for NP_082155.1

      Status: VALIDATED

      Source sequence(s)
      AA163414, AK004569, BC158078, BE691319
      Consensus CDS
      CCDS48546.1
      UniProtKB/Swiss-Prot
      Q9DC48
      Related
      ENSMUSP00000044305.8, ENSMUST00000044166.9
      Conserved Domains (2) summary
      cd00200
      Location:281579
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:292330
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      40707617..40759139 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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