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    Cdc5l cell division cycle 5-like (S. pombe) [ Mus musculus (house mouse) ]

    Gene ID: 71702, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cdc5lprovided by MGI
    Official Full Name
    cell division cycle 5-like (S. pombe)provided by MGI
    Primary source
    MGI:MGI:1918952
    See related
    Ensembl:ENSMUSG00000023932
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PCDC5RP; AA408004; 1200002I02Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 14.3), CNS E14 (RPKM 10.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cdc5l in Genome Data Viewer
    Location:
    17; 17 B3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (45391887..45433734, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (45528836..45570656, complement)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41582 Neighboring gene predicted gene, 35204 Neighboring gene RIKEN cDNA B230354K17 gene Neighboring gene spermatogenesis associated, serine-rich 1 Neighboring gene ribosomal protein L21 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    WD40-repeat domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    leucine zipper domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphatase 1 binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription corepressor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to nerve growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to wortmannin ISO
    Inferred from Sequence Orthology
    more info
     
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    signal transduction involved in DNA damage checkpoint ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    colocalizes_with DNA replication factor A complex ISO
    Inferred from Sequence Orthology
    more info
     
    Prp19 complex ISO
    Inferred from Sequence Orthology
    more info
     
    U2-type catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    protein-DNA complex ISO
    Inferred from Sequence Orthology
    more info
     
    spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cell division cycle 5-like protein
    Names
    cdc5-like protein
    cell division cycle 5-related protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152810.2NP_690023.1  cell division cycle 5-like protein

      See identical proteins and their annotated locations for NP_690023.1

      Status: PROVISIONAL

      Source sequence(s)
      AC163677, AC169676
      Consensus CDS
      CCDS37627.1
      UniProtKB/Swiss-Prot
      Q6A068
      UniProtKB/TrEMBL
      Q3UCF2
      Related
      ENSMUSP00000024727.8, ENSMUST00000024727.9
      Conserved Domains (4) summary
      smart00717
      Location:856
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11659
      Location:56106
      SANT_CDC5_II; SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II
      pfam11831
      Location:404655
      Myb_Cef; pre-mRNA splicing factor component
      pfam13921
      Location:1171
      Myb_DNA-bind_6; Myb-like DNA-binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      45391887..45433734 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017317643.1XP_017173132.1  cell division cycle 5-like protein isoform X1

      UniProtKB/TrEMBL
      Q05DT4
      Conserved Domains (3) summary
      smart00717
      Location:856
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11659
      Location:56106
      SANT_CDC5_II; SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II
      pfam13921
      Location:1171
      Myb_DNA-bind_6; Myb-like DNA-binding domain
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