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    Pds5a PDS5 cohesin associated factor A [ Mus musculus (house mouse) ]

    Gene ID: 71521, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pds5aprovided by MGI
    Official Full Name
    PDS5 cohesin associated factor Aprovided by MGI
    Primary source
    MGI:MGI:1918771
    See related
    Ensembl:ENSMUSG00000029202
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9030416H16Rik; B230308N11Rik; E230024D05Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 19.5), limb E14.5 (RPKM 12.4) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Pds5a in Genome Data Viewer
    Location:
    5; 5 C3.1
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (65763062..65855579, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (65605719..65698236, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (66006499..66089095, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 14 Neighboring gene predicted gene, 40309 Neighboring gene ubiquitin-conjugating enzyme E2K Neighboring gene predicted gene, 24399 Neighboring gene NEDD4 binding protein 2 Neighboring gene predicted gene 5296 Neighboring gene predicted gene 3521

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • mKIAA0648

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    sister chromatid cohesion protein PDS5 homolog A
    Names
    PDS5, regulator of cohesion maintenance, homolog A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081321.3NP_001074790.1  sister chromatid cohesion protein PDS5 homolog A

      See identical proteins and their annotated locations for NP_001074790.1

      Status: VALIDATED

      Source sequence(s)
      AC112263
      UniProtKB/TrEMBL
      E9QPI5
      Related
      ENSMUSP00000144171.2, ENSMUST00000201948.4
      Conserved Domains (1) summary
      sd00044
      Location:282312
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      65763062..65855579 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030254809.2XP_030110669.1  sister chromatid cohesion protein PDS5 homolog A isoform X2

      Conserved Domains (1) summary
      sd00044
      Location:99129
      HEAT; HEAT repeat [structural motif]
    2. XM_036165493.1XP_036021386.1  sister chromatid cohesion protein PDS5 homolog A isoform X3

      Conserved Domains (2) summary
      sd00044
      Location:99129
      HEAT; HEAT repeat [structural motif]
      cd19953
      Location:1487
      PDS5; Sister chromatid cohesion protein PDS5
    3. XM_006504115.5XP_006504178.1  sister chromatid cohesion protein PDS5 homolog A isoform X1

      See identical proteins and their annotated locations for XP_006504178.1

      Related
      ENSMUSP00000031104.7, ENSMUST00000031104.7
      Conserved Domains (1) summary
      sd00044
      Location:282312
      HEAT; HEAT repeat [structural motif]

    RNA

    1. XR_001784747.2 RNA Sequence

    2. XR_001784748.2 RNA Sequence

    3. XR_004942563.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_027818.1: Suppressed sequence

      Description
      NM_027818.1: This RefSeq was removed because currently there is insufficient support for the transcript.
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