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    Vps35l VPS35 endosomal protein sorting factor like [ Mus musculus (house mouse) ]

    Gene ID: 71517, updated on 27-Nov-2024

    Summary

    Official Symbol
    Vps35lprovided by MGI
    Official Full Name
    VPS35 endosomal protein sorting factor likeprovided by MGI
    Primary source
    MGI:MGI:1918767
    See related
    Ensembl:ENSMUSG00000030982 AllianceGenome:MGI:1918767
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Vsp35l; 2610029J22Rik; 9030624J02Rik
    Summary
    Predicted to be involved in Golgi to plasma membrane transport and endocytic recycling. Predicted to be located in membrane. Predicted to be active in endosome. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome. Orthologous to human VPS35L (VPS35 endosomal protein sorting factor like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 16.3), placenta adult (RPKM 15.9) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Vps35l in Genome Data Viewer
    Location:
    7 F2; 7 63.61 cM
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (118339401..118440712)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (118740178..118841491)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr7:125849164-125849465 Neighboring gene STARR-positive B cell enhancer ABC_E4970 Neighboring gene glycerophosphodiester phosphodiesterase 1 Neighboring gene centriolar coiled coil protein 110 Neighboring gene STARR-positive B cell enhancer ABC_E4971 Neighboring gene STARR-positive B cell enhancer ABC_E1359 Neighboring gene STARR-positive B cell enhancer mm9_chr7:125909648-125909949 Neighboring gene STARR-seq mESC enhancer starr_20020 Neighboring gene predicted gene, 26147 Neighboring gene STARR-seq mESC enhancer starr_20027 Neighboring gene lysine rich nucleolar protein 1 Neighboring gene IQ motif containing K Neighboring gene STARR-seq mESC enhancer starr_20029 Neighboring gene G protein-coupled receptor, family C, group 5, member B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in Golgi to plasma membrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endocytic recycling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endocytic recycling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endocytic recycling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    VPS35 endosomal protein-sorting factor-like
    Names
    UPF0505 protein C16orf62 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027815.5NP_082091.4  VPS35 endosomal protein-sorting factor-like

      Status: VALIDATED

      Source sequence(s)
      AC152412, AC165086
      Consensus CDS
      CCDS21776.2
      UniProtKB/Swiss-Prot
      Q3UWS3, Q3UXM0, Q7TQF5, Q80XN3, Q8BWQ6, Q8R3A8, Q91VY3, Q9D307
      Related
      ENSMUSP00000051263.8, ENSMUST00000059390.13

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      118339401..118440712
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508212.2XP_006508275.1  VPS35 endosomal protein-sorting factor-like isoform X1

      UniProtKB/TrEMBL
      I1E4X5

    RNA

    1. XR_378273.2 RNA Sequence