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    GSK3B glycogen synthase kinase 3 beta [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713114, updated on 17-Dec-2025
    Official Symbol
    GSK3Bprovided by VGNC
    Official Full Name
    glycogen synthase kinase 3 betaprovided by VGNC
    Primary source
    VGNC:VGNC:73298
    See related
    Ensembl:ENSMMUG00000001980
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    all
    Try the new Gene page
    Try the new Transcripts and proteins table
    See GSK3B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 2 NC_133407.1 (163634087..163903915)
    103 previous assembly Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (156183349..156453464)

    Chromosome 2 - NC_133407.1Genomic Context describing neighboring genes Neighboring gene prostate tumor-overexpressed gene 1 protein pseudogene Neighboring gene G protein-coupled receptor 156 Neighboring gene uncharacterized LOC144339403 Neighboring gene microRNA mir-6529 Neighboring gene presenilin-associated rhomboid-like protein, mitochondrial pseudogene Neighboring gene prohibitin 1 pseudogene Neighboring gene nuclear receptor subfamily 1 group I member 2

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables beta-catenin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tau-protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in insulin receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of TOR signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-threonine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of neuron projection development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of beta-catenin destruction complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Preferred Names
    glycogen synthase kinase-3 beta
    XP_014985446.1
    XP_028700433.1
    XP_028700434.1
    XP_028700435.1

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference T2T-MMU8v2.0

    Genomic

    1. NC_133407.1 Reference T2T-MMU8v2.0

      Range
      163634087..163903915
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015129960.3 → XP_014985446.1  glycogen synthase kinase-3 beta isoform X1

      UniProtKB/TrEMBL
      G7MKE9, H9EPM1
      Related
      ENSMMUP00000060644.1
      Conserved Domains (1) summary
      cd14137
      Location:51 → 356
      STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

    2. XM_028844600.2 → XP_028700433.1  glycogen synthase kinase-3 beta isoform X2

      UniProtKB/TrEMBL
      F6VAR2, G7MKE9, H9EPM2
      Related
      ENSMMUP00000002642.4
      Conserved Domains (1) summary
      cd14137
      Location:51 → 343
      STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

    3. XM_028844602.2 → XP_028700435.1  glycogen synthase kinase-3 beta isoform X4

      UniProtKB/TrEMBL
      G7MKE9
      Conserved Domains (1) summary
      cd14137
      Location:51 → 343
      STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

    4. XM_028844601.2 → XP_028700434.1  glycogen synthase kinase-3 beta isoform X3

      UniProtKB/TrEMBL
      A0A5F8A1A5, G7MKE9
      Related
      ENSMMUP00000070711.1
      Conserved Domains (1) summary
      cd14137
      Location:51 → 356
      STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
    Nucleotide Protein
    Heading Accession and Version

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