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    Lrrfip2 leucine rich repeat (in FLII) interacting protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 71268, updated on 23-Jun-2021

    Summary

    Official Symbol
    Lrrfip2provided by MGI
    Official Full Name
    leucine rich repeat (in FLII) interacting protein 2provided by MGI
    Primary source
    MGI:MGI:1918518
    See related
    Ensembl:ENSMUSG00000032497
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI850587; 5133400F20Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 12.8), placenta adult (RPKM 9.9) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Lrrfip2 in Genome Data Viewer
    Location:
    9; 9 F3
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (110946614..111054736)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (111117546..111225668)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (111020615..111128172)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L31, pseudogene 19 Neighboring gene predicted gene, 26409 Neighboring gene predicted gene, 53519 Neighboring gene uncharacterized LOC115487194 Neighboring gene predicted gene, 51692 Neighboring gene mutL homolog 1 Neighboring gene EPM2A (laforin) interacting protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    leucine-rich repeat flightless-interacting protein 2
    Names
    LRR FLII-interacting protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164838.1NP_001158310.1  leucine-rich repeat flightless-interacting protein 2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AC132832, AK078881, BY346593
      Consensus CDS
      CCDS52941.1
      UniProtKB/Swiss-Prot
      Q91WK0
      UniProtKB/TrEMBL
      E9QN52
      Related
      ENSMUSP00000035078.7, ENSMUST00000035078.13
      Conserved Domains (2) summary
      pfam04111
      Location:311405
      APG6; Autophagy protein Apg6
      pfam09738
      Location:47340
      LRRFIP; LRRFIP family
    2. NM_001374664.1NP_001361593.1  leucine-rich repeat flightless-interacting protein 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC132832
      Consensus CDS
      CCDS90673.1
      Related
      ENSMUSP00000142851.2, ENSMUST00000196981.5
      Conserved Domains (2) summary
      pfam09738
      Location:47349
      LRRFIP; LRRFIP family
      pfam11932
      Location:365424
      DUF3450; Protein of unknown function (DUF3450)
    3. NM_027742.3NP_082018.1  leucine-rich repeat flightless-interacting protein 2 isoform 2

      See identical proteins and their annotated locations for NP_082018.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an exon in the 5' coding region compared to variant 1 but maintains the reading frame. The resulting protein (isoform 2) is shorter than isoform 1.
      Source sequence(s)
      AC132832, AK078881, BY346593
      Consensus CDS
      CCDS23583.1
      UniProtKB/Swiss-Prot
      Q91WK0
      UniProtKB/TrEMBL
      A0A0R4J169
      Related
      ENSMUSP00000095944.3, ENSMUST00000098340.7
      Conserved Domains (2) summary
      pfam04111
      Location:296390
      APG6; Autophagy protein Apg6
      pfam09738
      Location:47325
      LRRFIP; LRRFIP family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      110946614..111054736
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011243000.3XP_011241302.1  leucine-rich repeat flightless-interacting protein 2 isoform X1

      Conserved Domains (3) summary
      TIGR04211
      Location:465549
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:319673
      LRRFIP; LRRFIP family
      pfam11932
      Location:689748
      DUF3450; Protein of unknown function (DUF3450)
    2. XM_036155284.1XP_036011177.1  leucine-rich repeat flightless-interacting protein 2 isoform X7

      Conserved Domains (2) summary
      pfam09738
      Location:319642
      LRRFIP; LRRFIP family
      pfam11932
      Location:658717
      DUF3450; Protein of unknown function (DUF3450)
    3. XM_017313589.3XP_017169078.1  leucine-rich repeat flightless-interacting protein 2 isoform X15

      Conserved Domains (2) summary
      pfam09738
      Location:319608
      LRRFIP; LRRFIP family
      pfam11932
      Location:624683
      DUF3450; Protein of unknown function (DUF3450)
    4. XM_011243004.3XP_011241306.1  leucine-rich repeat flightless-interacting protein 2 isoform X5

      Conserved Domains (3) summary
      TIGR04211
      Location:441525
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:319649
      LRRFIP; LRRFIP family
      pfam11932
      Location:665724
      DUF3450; Protein of unknown function (DUF3450)
    5. XM_017313590.3XP_017169079.1  leucine-rich repeat flightless-interacting protein 2 isoform X17

      Conserved Domains (2) summary
      pfam09738
      Location:319584
      LRRFIP; LRRFIP family
      pfam11932
      Location:600659
      DUF3450; Protein of unknown function (DUF3450)
    6. XM_036155286.1XP_036011179.1  leucine-rich repeat flightless-interacting protein 2 isoform X14

      Conserved Domains (2) summary
      pfam09738
      Location:286609
      LRRFIP; LRRFIP family
      pfam11932
      Location:625684
      DUF3450; Protein of unknown function (DUF3450)
    7. XM_030244586.1XP_030100446.1  leucine-rich repeat flightless-interacting protein 2 isoform X16

      Conserved Domains (2) summary
      pfam09738
      Location:301600
      LRRFIP; LRRFIP family
      pfam11932
      Location:616675
      DUF3450; Protein of unknown function (DUF3450)
    8. XM_036155287.1XP_036011180.1  leucine-rich repeat flightless-interacting protein 2 isoform X22

      Conserved Domains (2) summary
      pfam09738
      Location:196485
      LRRFIP; LRRFIP family
      pfam11932
      Location:501560
      DUF3450; Protein of unknown function (DUF3450)
    9. XM_030244588.2XP_030100448.1  leucine-rich repeat flightless-interacting protein 2 isoform X24

      Conserved Domains (2) summary
      pfam09738
      Location:196461
      LRRFIP; LRRFIP family
      pfam11932
      Location:477536
      DUF3450; Protein of unknown function (DUF3450)
    10. XM_030244589.1XP_030100449.1  leucine-rich repeat flightless-interacting protein 2 isoform X26

      Conserved Domains (2) summary
      pfam09738
      Location:47435
      LRRFIP; LRRFIP family
      pfam11932
      Location:451510
      DUF3450; Protein of unknown function (DUF3450)
    11. XM_030244591.1XP_030100451.1  leucine-rich repeat flightless-interacting protein 2 isoform X31

      Conserved Domains (2) summary
      pfam09738
      Location:47411
      LRRFIP; LRRFIP family
      pfam11932
      Location:427486
      DUF3450; Protein of unknown function (DUF3450)
    12. XM_011243024.3XP_011241326.1  leucine-rich repeat flightless-interacting protein 2 isoform X32

      Conserved Domains (3) summary
      TIGR04211
      Location:197281
      SH3_and_anchor; SH3 domain protein
      pfam05266
      Location:380454
      DUF724; Protein of unknown function (DUF724)
      pfam09738
      Location:47405
      LRRFIP; LRRFIP family
    13. XM_011243026.3XP_011241328.1  leucine-rich repeat flightless-interacting protein 2 isoform X43

      Conserved Domains (2) summary
      pfam09738
      Location:267532
      LRRFIP; LRRFIP family
      pfam11932
      Location:548607
      DUF3450; Protein of unknown function (DUF3450)
    14. XM_030244587.2XP_030100447.1  leucine-rich repeat flightless-interacting protein 2 isoform X20

      Conserved Domains (2) summary
      pfam09738
      Location:200489
      LRRFIP; LRRFIP family
      pfam11932
      Location:505564
      DUF3450; Protein of unknown function (DUF3450)
    15. XM_036155288.1XP_036011181.1  leucine-rich repeat flightless-interacting protein 2 isoform X35

      Conserved Domains (2) summary
      pfam09738
      Location:47380
      LRRFIP; LRRFIP family
      pfam11932
      Location:396455
      DUF3450; Protein of unknown function (DUF3450)
    16. XM_017313591.3XP_017169080.1  leucine-rich repeat flightless-interacting protein 2 isoform X34

      Conserved Domains (2) summary
      pfam05266
      Location:358432
      DUF724; Protein of unknown function (DUF724)
      pfam09738
      Location:47383
      LRRFIP; LRRFIP family
    17. XM_030244593.1XP_030100453.1  leucine-rich repeat flightless-interacting protein 2 isoform X33

      Conserved Domains (3) summary
      TIGR04211
      Location:182266
      SH3_and_anchor; SH3 domain protein
      pfam05266
      Location:365439
      DUF724; Protein of unknown function (DUF724)
      pfam09738
      Location:47390
      LRRFIP; LRRFIP family
    18. XM_036155289.1XP_036011182.1  leucine-rich repeat flightless-interacting protein 2 isoform X39

      Conserved Domains (2) summary
      pfam09738
      Location:47356
      LRRFIP; LRRFIP family
      pfam11932
      Location:372431
      DUF3450; Protein of unknown function (DUF3450)
    19. XM_030244596.1XP_030100456.1  leucine-rich repeat flightless-interacting protein 2 isoform X38

      Conserved Domains (2) summary
      pfam09738
      Location:47359
      LRRFIP; LRRFIP family
      pfam11932
      Location:375434
      DUF3450; Protein of unknown function (DUF3450)
    20. XM_011243001.4XP_011241303.1  leucine-rich repeat flightless-interacting protein 2 isoform X2

      Related
      ENSMUSP00000159250.2, ENSMUST00000239186.2
      Conserved Domains (3) summary
      TIGR04211
      Location:462546
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:316670
      LRRFIP; LRRFIP family
      pfam11932
      Location:686745
      DUF3450; Protein of unknown function (DUF3450)
    21. XM_036155285.1XP_036011178.1  leucine-rich repeat flightless-interacting protein 2 isoform X9

      Conserved Domains (2) summary
      pfam09738
      Location:286640
      LRRFIP; LRRFIP family
      pfam11932
      Location:656715
      DUF3450; Protein of unknown function (DUF3450)
    22. XM_011243005.4XP_011241307.1  leucine-rich repeat flightless-interacting protein 2 isoform X6

      Conserved Domains (3) summary
      TIGR04211
      Location:439523
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:293647
      LRRFIP; LRRFIP family
      pfam11932
      Location:663722
      DUF3450; Protein of unknown function (DUF3450)
    23. XM_011243012.4XP_011241314.1  leucine-rich repeat flightless-interacting protein 2 isoform X13

      Conserved Domains (3) summary
      TIGR04211
      Location:409493
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:263617
      LRRFIP; LRRFIP family
      pfam11932
      Location:633692
      DUF3450; Protein of unknown function (DUF3450)
    24. XM_011243003.4XP_011241305.1  leucine-rich repeat flightless-interacting protein 2 isoform X4

      Conserved Domains (3) summary
      TIGR04211
      Location:446530
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:300654
      LRRFIP; LRRFIP family
      pfam11932
      Location:670729
      DUF3450; Protein of unknown function (DUF3450)
    25. XM_011243002.4XP_011241304.1  leucine-rich repeat flightless-interacting protein 2 isoform X3

      Conserved Domains (3) summary
      TIGR04211
      Location:450534
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:304658
      LRRFIP; LRRFIP family
      pfam11932
      Location:674733
      DUF3450; Protein of unknown function (DUF3450)
    26. XM_011243008.4XP_011241310.1  leucine-rich repeat flightless-interacting protein 2 isoform X10

      Conserved Domains (3) summary
      TIGR04211
      Location:431515
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:285639
      LRRFIP; LRRFIP family
      pfam11932
      Location:655714
      DUF3450; Protein of unknown function (DUF3450)
    27. XM_011243007.4XP_011241309.1  leucine-rich repeat flightless-interacting protein 2 isoform X8

      Conserved Domains (3) summary
      TIGR04211
      Location:433517
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:287641
      LRRFIP; LRRFIP family
      pfam11932
      Location:657716
      DUF3450; Protein of unknown function (DUF3450)
    28. XM_011243016.4XP_011241318.1  leucine-rich repeat flightless-interacting protein 2 isoform X18

      Conserved Domains (3) summary
      TIGR04211
      Location:342426
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:196550
      LRRFIP; LRRFIP family
      pfam11932
      Location:566625
      DUF3450; Protein of unknown function (DUF3450)
    29. XM_011243017.4XP_011241319.1  leucine-rich repeat flightless-interacting protein 2 isoform X19

      Conserved Domains (3) summary
      TIGR04211
      Location:337421
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:191545
      LRRFIP; LRRFIP family
      pfam11932
      Location:561620
      DUF3450; Protein of unknown function (DUF3450)
    30. XM_011243018.4XP_011241320.1  leucine-rich repeat flightless-interacting protein 2 isoform X21

      Conserved Domains (3) summary
      TIGR04211
      Location:281365
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:135489
      LRRFIP; LRRFIP family
      pfam11932
      Location:505564
      DUF3450; Protein of unknown function (DUF3450)
    31. XM_011243019.4XP_011241321.1  leucine-rich repeat flightless-interacting protein 2 isoform X23

      Conserved Domains (3) summary
      TIGR04211
      Location:258342
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:47466
      LRRFIP; LRRFIP family
      pfam11932
      Location:482541
      DUF3450; Protein of unknown function (DUF3450)
    32. XM_011243010.4XP_011241312.1  leucine-rich repeat flightless-interacting protein 2 isoform X11

      Conserved Domains (3) summary
      TIGR04211
      Location:428512
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:282636
      LRRFIP; LRRFIP family
      pfam11932
      Location:652711
      DUF3450; Protein of unknown function (DUF3450)
    33. XM_011243021.4XP_011241323.1  leucine-rich repeat flightless-interacting protein 2 isoform X27

      Conserved Domains (3) summary
      TIGR04211
      Location:221305
      SH3_and_anchor; SH3 domain protein
      pfam05266
      Location:404478
      DUF724; Protein of unknown function (DUF724)
      pfam09738
      Location:47429
      LRRFIP; LRRFIP family
    34. XM_011243011.4XP_011241313.1  leucine-rich repeat flightless-interacting protein 2 isoform X12

      Related
      ENSMUSP00000149845.3, ENSMUST00000217341.3
      Conserved Domains (3) summary
      TIGR04211
      Location:413497
      SH3_and_anchor; SH3 domain protein
      pfam09738
      Location:267621
      LRRFIP; LRRFIP family
      pfam11932
      Location:637696
      DUF3450; Protein of unknown function (DUF3450)
    35. XM_011243020.4XP_011241322.1  leucine-rich repeat flightless-interacting protein 2 isoform X25

      Conserved Domains (3) summary
      TIGR04211
      Location:229313
      SH3_and_anchor; SH3 domain protein
      pfam05266
      Location:412486
      DUF724; Protein of unknown function (DUF724)
      pfam09738
      Location:47437
      LRRFIP; LRRFIP family
    36. XM_011243023.4XP_011241325.1  leucine-rich repeat flightless-interacting protein 2 isoform X30

      Conserved Domains (3) summary
      TIGR04211
      Location:206290
      SH3_and_anchor; SH3 domain protein
      pfam05266
      Location:389463
      DUF724; Protein of unknown function (DUF724)
      pfam09738
      Location:47414
      LRRFIP; LRRFIP family
    37. XM_011243022.4XP_011241324.1  leucine-rich repeat flightless-interacting protein 2 isoform X28

      Conserved Domains (1) summary
      pfam09738
      Location:319484
      LRRFIP; LRRFIP family
    38. XM_006512287.4XP_006512350.1  leucine-rich repeat flightless-interacting protein 2 isoform X29

      Conserved Domains (3) summary
      TIGR04211
      Location:212296
      SH3_and_anchor; SH3 domain protein
      pfam05266
      Location:395469
      DUF724; Protein of unknown function (DUF724)
      pfam09738
      Location:66420
      LRRFIP; LRRFIP family
    39. XM_030244598.2XP_030100458.1  leucine-rich repeat flightless-interacting protein 2 isoform X41

      Related
      ENSMUSP00000149212.2, ENSMUST00000216430.2
      Conserved Domains (2) summary
      pfam09738
      Location:36301
      LRRFIP; LRRFIP family
      pfam11932
      Location:317376
      DUF3450; Protein of unknown function (DUF3450)
    40. XM_030244595.2XP_030100455.1  leucine-rich repeat flightless-interacting protein 2 isoform X37

      Related
      ENSMUST00000197540.5
      Conserved Domains (3) summary
      TIGR04211
      Location:155239
      SH3_and_anchor; SH3 domain protein
      pfam05266
      Location:338412
      DUF724; Protein of unknown function (DUF724)
      pfam09738
      Location:33363
      LRRFIP; LRRFIP family
    41. XM_030244599.2XP_030100459.1  leucine-rich repeat flightless-interacting protein 2 isoform X42

      Related
      ENSMUSP00000151145.2, ENSMUST00000217117.2
      Conserved Domains (2) summary
      pfam09738
      Location:33298
      LRRFIP; LRRFIP family
      pfam11932
      Location:314373
      DUF3450; Protein of unknown function (DUF3450)
    42. XM_030244597.1XP_030100457.1  leucine-rich repeat flightless-interacting protein 2 isoform X40

      Conserved Domains (2) summary
      pfam09738
      Location:13309
      LRRFIP; LRRFIP family
      pfam11932
      Location:325384
      DUF3450; Protein of unknown function (DUF3450)
    43. XM_006512290.2XP_006512353.1  leucine-rich repeat flightless-interacting protein 2 isoform X36

      Conserved Domains (3) summary
      TIGR04211
      Location:159243
      SH3_and_anchor; SH3 domain protein
      pfam05266
      Location:342416
      DUF724; Protein of unknown function (DUF724)
      pfam09738
      Location:13367
      LRRFIP; LRRFIP family
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