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    Pcgf6 polycomb group ring finger 6 [ Mus musculus (house mouse) ]

    Gene ID: 71041, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pcgf6provided by MGI
    Official Full Name
    polycomb group ring finger 6provided by MGI
    Primary source
    MGI:MGI:1918291
    See related
    Ensembl:ENSMUSG00000025050
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MB; MBLR; Rnf1; Rnf134; AI604840; 4933407A11Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 18.0), whole brain E14.5 (RPKM 15.5) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pcgf6 in Genome Data Viewer
    Location:
    19; 19 C3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (47022056..47039379, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (47033617..47050939, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (47108109..47125335, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene 5'-nucleotidase, cytosolic II Neighboring gene lysophosphatidic acid receptor 1 pseudogene Neighboring gene internexin neuronal intermediate filament protein, alpha Neighboring gene predicted gene, 23140 Neighboring gene TATA-box binding protein associated factor 5 Neighboring gene ATP synthase membrane subunit DAPIT

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC106622

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of PRC1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of PRC1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of PcG protein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of PcG protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    polycomb group RING finger protein 6
    Names
    Mel18- and Bmi1-like RING finger protein
    ring finger protein 134

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360632.1NP_001347561.1  polycomb group RING finger protein 6 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC108814, BC089460
      Conserved Domains (2) summary
      pfam16207
      Location:284331
      RAWUL; RAWUL domain RING finger- and WD40-associated ubiquitin-like
      cd16738
      Location:133177
      RING-HC_PCGF6; RING finger found in polycomb group RING finger protein 6 (PCGF6) and similar proteins
    2. NM_027654.3NP_081930.1  polycomb group RING finger protein 6 isoform 1

      See identical proteins and their annotated locations for NP_081930.1

      Status: VALIDATED

      Source sequence(s)
      AC108814, BC089460
      Consensus CDS
      CCDS29885.1
      UniProtKB/Swiss-Prot
      Q99NA9
      Related
      ENSMUSP00000026032.6, ENSMUST00000026032.7
      Conserved Domains (2) summary
      pfam00097
      Location:137175
      zf-C3HC4; Zinc finger, C3HC4 type (RING finger)
      pfam16207
      Location:266322
      RAWUL; RAWUL domain RING finger- and WD40-associated ubiquitin-like

    RNA

    1. NR_133574.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC108814, BC089460
      Related
      ENSMUST00000235633.2
    2. NR_153762.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC108814, BC089460

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      47022056..47039379 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527338.5XP_006527401.1  polycomb group RING finger protein 6 isoform X1

      Conserved Domains (2) summary
      cd16738
      Location:133177
      RING-HC_PCGF6; RING finger found in polycomb group RING finger protein 6 (PCGF6) and similar proteins
      cl28922
      Location:255313
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    2. XM_030251075.1XP_030106935.1  polycomb group RING finger protein 6 isoform X2

      Conserved Domains (2) summary
      cd16738
      Location:133177
      RING-HC_PCGF6; RING finger found in polycomb group RING finger protein 6 (PCGF6) and similar proteins
      cd17085
      Location:255307
      RAWUL_PCGF6; RING finger- and WD40-associated ubiquitin-like (RAWUL) domain found in polycomb group RING finger protein 6 (PCGF6) and similar proteins
    3. XM_036161687.1XP_036017580.1  polycomb group RING finger protein 6 isoform X3

      Conserved Domains (1) summary
      cd16738
      Location:133177
      RING-HC_PCGF6; RING finger found in polycomb group RING finger protein 6 (PCGF6) and similar proteins

    RNA

    1. XR_001782614.3 RNA Sequence

    2. XR_386508.5 RNA Sequence

    3. XR_003952816.1 RNA Sequence

    4. XR_003952814.1 RNA Sequence

    5. XR_004940173.1 RNA Sequence

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