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    D7Ertd443e DNA segment, Chr 7, ERATO Doi 443, expressed [ Mus musculus (house mouse) ]

    Gene ID: 71007, updated on 2-Aug-2021

    Summary

    Official Symbol
    D7Ertd443eprovided by MGI
    Official Full Name
    DNA segment, Chr 7, ERATO Doi 443, expressedprovided by MGI
    Primary source
    MGI:MGI:1196431
    See related
    Ensembl:ENSMUSG00000030994
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FATS; Gm497; 4933400E14Rik
    Expression
    Biased expression in testis adult (RPKM 9.5) and cerebellum adult (RPKM 0.7) See more
    Orthologs
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    Genomic context

    See D7Ertd443e in Genome Data Viewer
    Location:
    7 F3; 7 78.4 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (133867509..134121888, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (134265780..134520159, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (141457945..141568511, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene a disintegrin and metallopeptidase domain 12 (meltrin alpha) Neighboring gene predicted gene, 51500 Neighboring gene predicted gene, 39103 Neighboring gene predicted gene, 35970 Neighboring gene methionine aminopeptidase 2 pseudogene Neighboring gene dedicator of cytokinesis 1 Neighboring gene inhibitory synaptic factor 2A

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables histone deacetylase binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    (E2-independent) E3 ubiquitin-conjugating enzyme FATS
    Names
    E2/E3 hybrid ubiquitin-protein ligase FATS
    centrosomal protein C10orf90 homolog
    fragile-site associated tumor suppressor homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081331.2NP_001074800.1  (E2-independent) E3 ubiquitin-conjugating enzyme FATS isoform 2

      See identical proteins and their annotated locations for NP_001074800.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC124369, AC126676
      Consensus CDS
      CCDS57590.1
      UniProtKB/Swiss-Prot
      D2J0Y4
      Related
      ENSMUSP00000091539.4, ENSMUST00000094002.10
      Conserved Domains (2) summary
      pfam15309
      Location:514641
      ALMS_motif; ALMS motif
      pfam17730
      Location:5509
      Centro_C10orf90; Centrosomal C10orf90
    2. NM_001199941.1NP_001186870.1  (E2-independent) E3 ubiquitin-conjugating enzyme FATS isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      GQ499374
      Consensus CDS
      CCDS57591.1
      UniProtKB/Swiss-Prot
      D2J0Y4
      UniProtKB/TrEMBL
      G3UZF7
      Related
      ENSMUSP00000134479.2, ENSMUST00000172947.8
      Conserved Domains (1) summary
      pfam15309
      Location:561689
      ALMS_motif; ALMS motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      133867509..134121888 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241903.3XP_011240205.1  (E2-independent) E3 ubiquitin-conjugating enzyme FATS isoform X3

      Conserved Domains (2) summary
      pfam15309
      Location:530657
      ALMS_motif; ALMS motif
      pfam17730
      Location:21525
      Centro_C10orf90; Centrosomal C10orf90
    2. XM_011241905.4XP_011240207.1  (E2-independent) E3 ubiquitin-conjugating enzyme FATS isoform X4

      See identical proteins and their annotated locations for XP_011240207.1

      UniProtKB/Swiss-Prot
      D2J0Y4
      Conserved Domains (2) summary
      pfam15309
      Location:514641
      ALMS_motif; ALMS motif
      pfam17730
      Location:5509
      Centro_C10orf90; Centrosomal C10orf90
    3. XM_011241901.2XP_011240203.1  (E2-independent) E3 ubiquitin-conjugating enzyme FATS isoform X1

      See identical proteins and their annotated locations for XP_011240203.1

      Conserved Domains (2) summary
      pfam15309
      Location:591718
      ALMS_motif; ALMS motif
      pfam17730
      Location:82586
      Centro_C10orf90; Centrosomal C10orf90
    4. XM_011241906.3XP_011240208.1  (E2-independent) E3 ubiquitin-conjugating enzyme FATS isoform X5

      Conserved Domains (2) summary
      pfam15309
      Location:496623
      ALMS_motif; ALMS motif
      pfam17730
      Location:82491
      Centro_C10orf90; Centrosomal C10orf90
    5. XM_011241902.4XP_011240204.1  (E2-independent) E3 ubiquitin-conjugating enzyme FATS isoform X2

      Conserved Domains (2) summary
      pfam15309
      Location:545672
      ALMS_motif; ALMS motif
      pfam17730
      Location:36540
      Centro_C10orf90; Centrosomal C10orf90
    6. XM_011241904.4XP_011240206.1  (E2-independent) E3 ubiquitin-conjugating enzyme FATS isoform X4

      See identical proteins and their annotated locations for XP_011240206.1

      UniProtKB/Swiss-Prot
      D2J0Y4
      Conserved Domains (2) summary
      pfam15309
      Location:514641
      ALMS_motif; ALMS motif
      pfam17730
      Location:5509
      Centro_C10orf90; Centrosomal C10orf90
    7. XM_011241907.4XP_011240209.1  (E2-independent) E3 ubiquitin-conjugating enzyme FATS isoform X6

      See identical proteins and their annotated locations for XP_011240209.1

      UniProtKB/TrEMBL
      Q9D4E0
      Related
      ENSMUSP00000101735.3, ENSMUST00000106129.9
      Conserved Domains (2) summary
      pfam15309
      Location:155282
      ALMS_motif; ALMS motif
      pfam17730
      Location:3150
      Centro_C10orf90; Centrosomal C10orf90
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