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    Naa40 N(alpha)-acetyltransferase 40, NatD catalytic subunit [ Mus musculus (house mouse) ]

    Gene ID: 70999, updated on 23-Jun-2021

    Summary

    Official Symbol
    Naa40provided by MGI
    Official Full Name
    N(alpha)-acetyltransferase 40, NatD catalytic subunitprovided by MGI
    Primary source
    MGI:MGI:1918249
    See related
    Ensembl:ENSMUSG00000024764
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nat; NatD; Nat11; AU023197; 4931433E08Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 26.2), whole brain E14.5 (RPKM 19.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Naa40 in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (7203033..7218587, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (7225668..7241222, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (7300158..7315712, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene OTU domain, ubiquitin aldehyde binding 1 Neighboring gene cytochrome c oxidase subunit 8A Neighboring gene predicted gene, 22113 Neighboring gene REST corepressor 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables H2A histone acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables H2A histone acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables H4 histone acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables H4 histone acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptide-serine-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables peptide-serine-N-acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in N-terminal protein amino acid acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone H2A acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in histone H2A acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone H4 acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in histone H4 acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within lipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    N-alpha-acetyltransferase 40
    Names
    N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog
    N-acetyltransferase 11
    N-alpha-acetyltransferase D
    Nalpha acetyltransferase 40
    natD catalytic subunit
    protein acetyltransferase 1
    NP_081919.1
    XP_006527399.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027643.1NP_081919.1  N-alpha-acetyltransferase 40

      See identical proteins and their annotated locations for NP_081919.1

      Status: VALIDATED

      Source sequence(s)
      AK033510, AK033896, BB112808, BY107005
      Consensus CDS
      CCDS50377.1
      UniProtKB/Swiss-Prot
      Q8VE10
      Related
      ENSMUSP00000025675.10, ENSMUST00000025675.11
      Conserved Domains (1) summary
      pfam00583
      Location:80188
      Acetyltransf_1; Acetyltransferase (GNAT) family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      7203033..7218587 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527336.5XP_006527399.1  N-alpha-acetyltransferase 40 isoform X1

      Conserved Domains (1) summary
      cl17182
      Location:94135
      NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
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