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    Cdkn2aip CDKN2A interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 70925, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cdkn2aipprovided by MGI
    Official Full Name
    CDKN2A interacting proteinprovided by MGI
    Primary source
    MGI:MGI:1918175
    See related
    Ensembl:ENSMUSG00000038069
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CARF; AW208986; 4921511I16Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 14.7), CNS E11.5 (RPKM 5.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cdkn2aip in Genome Data Viewer
    Location:
    8; 8 B1.1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (47709344..47714854, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (48794698..48799285, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene inhibitor of growth family, member 2 Neighboring gene predicted gene, 31692 Neighboring gene predicted gene, 31638 Neighboring gene predicted gene, 31786 Neighboring gene RIKEN cDNA 1700061N14 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    p53 binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cellular response to DNA damage stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell growth ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell growth ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of protein stability ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    granular component ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    CDKN2A-interacting protein
    Names
    collaborates/cooperates with ARF (alternate reading frame) protein
    collaborator of ARF

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359133.1NP_001346062.1  CDKN2A-interacting protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC158316
    2. NM_172407.3NP_765995.1  CDKN2A-interacting protein isoform 1

      See identical proteins and their annotated locations for NP_765995.1

      Status: VALIDATED

      Source sequence(s)
      AK048437, AK078329, AK133831
      Consensus CDS
      CCDS22299.1
      UniProtKB/Swiss-Prot
      Q8BI72
      Related
      ENSMUSP00000148441.1, ENSMUST00000212175.1
      Conserved Domains (1) summary
      pfam11952
      Location:19117
      XTBD; XRN-Two Binding Domain, XTBD

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      47709344..47714854 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509489.2XP_006509552.1  CDKN2A-interacting protein isoform X1

      UniProtKB/TrEMBL
      A0A1I7Q4A1
      Related
      ENSMUSP00000043713.6, ENSMUST00000038738.6
      Conserved Domains (1) summary
      pfam11952
      Location:19117
      XTBD; XRN-Two Binding Domain, XTBD
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