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    Pgrmc2 progesterone receptor membrane component 2 [ Mus musculus (house mouse) ]

    Gene ID: 70804, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pgrmc2provided by MGI
    Official Full Name
    progesterone receptor membrane component 2provided by MGI
    Primary source
    MGI:MGI:1918054
    See related
    Ensembl:ENSMUSG00000049940
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DG6; PMBP; 4631434O19Rik; 5730409G06Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 16.9), ovary adult (RPKM 16.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Pgrmc2 in Genome Data Viewer
    Location:
    3; 3 B
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (41020761..41037481, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (41066326..41083046, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (40870248..40886968, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene La ribonucleoprotein domain family, member 1B Neighboring gene predicted gene, 22043 Neighboring gene predicted gene 42437 Neighboring gene predicted gene, 40038 Neighboring gene RIKEN cDNA 1700052H01 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables heme binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables heme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables heme transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables steroid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in adipose tissue development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in heme transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    membrane-associated progesterone receptor component 2
    Names
    progesterone membrane binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027558.1NP_081834.1  membrane-associated progesterone receptor component 2

      See identical proteins and their annotated locations for NP_081834.1

      Status: VALIDATED

      Source sequence(s)
      AK014543, AK140064, BE984949, CD363842
      Consensus CDS
      CCDS50899.1
      UniProtKB/Swiss-Prot
      Q80UU9
      Related
      ENSMUSP00000056643.8, ENSMUST00000058578.8
      Conserved Domains (1) summary
      pfam00173
      Location:96194
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      41020761..41037481 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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