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    Cep192 centrosomal protein 192 [ Mus musculus (house mouse) ]

    Gene ID: 70799, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cep192provided by MGI
    Official Full Name
    centrosomal protein 192provided by MGI
    Primary source
    MGI:MGI:1918049
    See related
    Ensembl:ENSMUSG00000024542
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4631422C13Rik; D430014P18Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 7.7), limb E14.5 (RPKM 5.8) and 25 other tissues See more
    Orthologs

    Genomic context

    See Cep192 in Genome Data Viewer
    Location:
    18; 18 E1
    Exon count:
    48
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 18 NC_000084.6 (67800101..67885170)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (67959761..68044824)

    Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930549G23 gene Neighboring gene predicted gene, 26910 Neighboring gene SEH1-like (S. cerevisiae Neighboring gene tubulin, alpha 1B pseudogene Neighboring gene low density lipoprotein receptor class A domain containing 4 Neighboring gene ribosomal protein L17 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    centrosome-templated microtubule nucleation ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule nucleation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    mitotic spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle assembly checkpoint ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of centriole replication ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of centrosome cycle ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of establishment of protein localization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    response to bacterium IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    centriole ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    centrosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    pericentriolar material IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    centrosomal protein of 192 kDa

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027556.1NP_081832.1  centrosomal protein of 192 kDa

      Status: VALIDATED

      Source sequence(s)
      AC127236, AK052420, AK158414, BC064462, BE982606, CD538408, CK391255, CK639048, CO045915
      Consensus CDS
      CCDS50313.1
      UniProtKB/TrEMBL
      E9Q4Y4, Q6P2K8, Q8C769
      Related
      ENSMUSP00000025425.5, ENSMUST00000025425.6
      Conserved Domains (1) summary
      cl13764
      Location:16361703
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000084.6 Reference GRCm38.p4 C57BL/6J

      Range
      67800101..67885170
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247001.2XP_011245303.1  centrosomal protein of 192 kDa isoform X4

      Conserved Domains (1) summary
      cl13764
      Location:16361698
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
    2. XM_006526242.2XP_006526305.1  centrosomal protein of 192 kDa isoform X1

      See identical proteins and their annotated locations for XP_006526305.1

      Conserved Domains (1) summary
      cl13764
      Location:16361703
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
    3. XM_006526241.2XP_006526304.1  centrosomal protein of 192 kDa isoform X1

      See identical proteins and their annotated locations for XP_006526304.1

      Conserved Domains (1) summary
      cl13764
      Location:16361703
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
    4. XM_006526243.2XP_006526306.1  centrosomal protein of 192 kDa isoform X2

      Conserved Domains (1) summary
      cl13764
      Location:15931660
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
    5. XM_011247000.2XP_011245302.1  centrosomal protein of 192 kDa isoform X3

      Conserved Domains (1) summary
      cl13764
      Location:10041066
      ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
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