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    Nolc1 nucleolar and coiled-body phosphoprotein 1 [ Mus musculus (house mouse) ]

    Gene ID: 70769, updated on 23-Jun-2021

    Summary

    Official Symbol
    Nolc1provided by MGI
    Official Full Name
    nucleolar and coiled-body phosphoprotein 1provided by MGI
    Primary source
    MGI:MGI:1918019
    See related
    Ensembl:ENSMUSG00000015176
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NOP; P13; P130; NOPP130; NOPP140
    Expression
    Broad expression in liver E14 (RPKM 39.7), liver E14.5 (RPKM 31.2) and 23 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Nolc1 in Genome Data Viewer
    Location:
    19; 19 C3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (46064286..46073982)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (46075847..46085543)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (46150353..46160020)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene ES cell cis-regulatory motif 2c Neighboring gene peroxisome proliferative activated receptor, gamma, coactivator-related 1 Neighboring gene elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 Neighboring gene paired-like homeodomain transcription factor 3 Neighboring gene golgi-specific brefeldin A-resistance factor 1 Neighboring gene U1 small nuclear ribonucleoprotein C pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • mKIAA0035, 3230402K17Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables TFIIB-class transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables box C/D RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables box C/D snoRNP complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables box H/ACA snoRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables box H/ACA snoRNP complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nuclear localization sequence binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-macromolecule adaptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Cajal body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of box C/D RNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of box H/ACA snoRNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of small nuclear ribonucleoprotein complex TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    nucleolar and coiled-body phosphoprotein 1
    Names
    140 kDa nucleolar phosphoprotein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039351.2NP_001034440.1  nucleolar and coiled-body phosphoprotein 1 isoform B

      See identical proteins and their annotated locations for NP_001034440.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses two alternate in-frame splice sites in the central coding region, compared to variant 3. The encoded isoform (B) is shorter, compared to isoform C.
      Source sequence(s)
      AK029150, AK147118, BE992617, BY031361
      Consensus CDS
      CCDS89406.1
      UniProtKB/Swiss-Prot
      E9Q5C9
      UniProtKB/TrEMBL
      A0A286YDA2
      Related
      ENSMUSP00000153329.2, ENSMUST00000223728.2
      Conserved Domains (1) summary
      pfam05022
      Location:625691
      SRP40_C; SRP40, C-terminal domain
    2. NM_001039352.2NP_001034441.1  nucleolar and coiled-body phosphoprotein 1 isoform C

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (C).
      Source sequence(s)
      AK034817, BE992617, BY031361, CF750495
      Consensus CDS
      CCDS38006.1
      UniProtKB/Swiss-Prot
      E9Q5C9
      Related
      ENSMUSP00000128331.2, ENSMUST00000165017.2
      Conserved Domains (1) summary
      pfam05022
      Location:627693
      SRP40_C; SRP40, C-terminal domain
    3. NM_001039353.2NP_001034442.1  nucleolar and coiled-body phosphoprotein 1 isoform D

      See identical proteins and their annotated locations for NP_001034442.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate in-frame splice site in the central coding region, compared to variant 3. The encoded isoform (D) is shorter, compared to isoform C.
      Source sequence(s)
      AK034817, AK147118, BE992617, BY031361
      UniProtKB/Swiss-Prot
      E9Q5C9
      Conserved Domains (1) summary
      pfam05022
      Location:626692
      SRP40_C; SRP40, C-terminal domain
    4. NM_053086.3NP_444316.2  nucleolar and coiled-body phosphoprotein 1 isoform A

      See identical proteins and their annotated locations for NP_444316.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) uses an alternate in-frame splice site in the central coding region, compared to variant 3. The encoded isoform (A) is shorter, compared to isoform C.
      Source sequence(s)
      AK147118, AK166753, BE992617, BY031361
      Consensus CDS
      CCDS89405.1
      UniProtKB/Swiss-Prot
      E9Q5C9
      UniProtKB/TrEMBL
      A0A286YDT3
      Related
      ENSMUSP00000153545.2, ENSMUST00000225780.2
      Conserved Domains (1) summary
      pfam05022
      Location:626692
      SRP40_C; SRP40, C-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      46064286..46073982
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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