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    SNCA synuclein alpha [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706985, updated on 17-Aug-2024
    Official Symbol
    SNCAprovided by VGNC
    Official Full Name
    synuclein alphaprovided by VGNC
    Primary source
    VGNC:VGNC:77668
    Locus tag
    EGK_15919
    See related
    Ensembl:ENSMMUG00000012123
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
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    See SNCA in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (88118358..88230916, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (88125924..88238817, complement)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene GPRIN family member 3 Neighboring gene multimerin 1 Neighboring gene coiled-coil serine rich protein 1

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain. Yang W, et al. J Neurosci, 2015 May 27. PMID 26019347, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Overexpression of mutant alpha-synuclein causes age-dependent pathological changes in brain.
      Title: Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain.
    Submit: New GeneRIF Correction

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cuprous ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of dopamine secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synapse organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic vesicle endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon terminus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Preferred Names
    alpha-synuclein
    Names
    Non-A beta component of AD amyloid
    alpha-synuclein-like

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      88118358..88230916 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015138786.2 → XP_014994272.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Related
      ENSMMUP00000068039.1, ENSMMUT00000104822.1
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    2. XM_015138787.2 → XP_014994273.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    3. XM_015138791.2 → XP_014994277.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Related
      ENSMMUP00000060035.2, ENSMMUT00000077846.2
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    4. XM_015138789.2 → XP_014994275.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    5. XM_015138785.2 → XP_014994271.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Related
      ENSMMUP00000073855.1, ENSMMUT00000097374.1
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    6. XM_015138784.2 → XP_014994270.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    7. XM_028848624.1 → XP_028704457.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    8. XM_015138783.2 → XP_014994269.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Related
      ENSMMUP00000050306.1, ENSMMUT00000061659.2
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    9. XM_028848623.1 → XP_028704456.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    10. XM_028848625.1 → XP_028704458.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    11. XM_015138788.2 → XP_014994274.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    12. XM_015138790.2 → XP_014994276.1  alpha-synuclein isoform X1

      UniProtKB/Swiss-Prot
      P61143
      UniProtKB/TrEMBL
      A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
      Related
      ENSMMUP00000015893.3, ENSMMUT00000016970.3
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 131
      Synuclein

    13. XM_028848626.1 → XP_028704459.1  alpha-synuclein isoform X2

      UniProtKB/TrEMBL
      A0A5F8AED5
      Related
      ENSMMUP00000076291.1, ENSMMUT00000089345.1
      Conserved Domains (1) summary
      pfam01387
      Location:1 → 104
      Synuclein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P61143.1 GenPept UniProtKB/Swiss-Prot:P61143

    Gene LinkOut

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