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    Atad2 ATPase family, AAA domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 70472, updated on 31-Jan-2019

    Summary

    Official Symbol
    Atad2provided by MGI
    Official Full Name
    ATPase family, AAA domain containing 2provided by MGI
    Primary source
    MGI:MGI:1917722
    See related
    Ensembl:ENSMUSG00000022360
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610509G12Rik
    Expression
    Broad expression in liver E14 (RPKM 11.8), CNS E11.5 (RPKM 11.6) and 19 other tissues See more
    Orthologs

    Genomic context

    See Atad2 in Genome Data Viewer
    Location:
    15; 15 D1
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (58094044..58135136, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (57925602..57966637, complement)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9130401M01 gene Neighboring gene zinc fingers and homeoboxes 1 Neighboring gene small nuclear ribonucleoprotein Sm D2 pseudogene Neighboring gene WDYHV motif containing 1 Neighboring gene predicted gene, 36112

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC38189

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of chromatin silencing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    ATPase family AAA domain-containing protein 2
    NP_081711.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027435.2NP_081711.2  ATPase family AAA domain-containing protein 2

      See identical proteins and their annotated locations for NP_081711.2

      Status: VALIDATED

      Source sequence(s)
      AK029867, AK032877, BC071261
      Consensus CDS
      CCDS37079.1
      UniProtKB/Swiss-Prot
      Q8CDM1
      UniProtKB/TrEMBL
      G3X963, Q6IQY4
      Related
      ENSMUSP00000043691.3, ENSMUST00000038194.4
      Conserved Domains (3) summary
      cd05528
      Location:9601070
      Bromo_AAA; Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The structure(2DKW) in this ...
      smart00382
      Location:438579
      AAA; ATPases associated with a variety of cellular activities
      pfam00004
      Location:443577
      AAA; ATPase family associated with various cellular activities (AAA)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      58094044..58135136 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_384045.3 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_153199.1: Suppressed sequence

      Description
      NM_153199.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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