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    Csnk1g3 casein kinase 1, gamma 3 [ Mus musculus (house mouse) ]

    Gene ID: 70425, updated on 25-Nov-2021

    Summary

    Official Symbol
    Csnk1g3provided by MGI
    Official Full Name
    casein kinase 1, gamma 3provided by MGI
    Primary source
    MGI:MGI:1917675
    See related
    Ensembl:ENSMUSG00000073563
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    3300002K07Rik; C330049O21Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 12.9), CNS E14 (RPKM 11.5) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Csnk1g3 in Genome Data Viewer
    Location:
    18; 18 D1- D2
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (53995154..54088756)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (53862082..53955684)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (54021767..54115338)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 19466 Neighboring gene centrosomal protein 120 Neighboring gene predicted gene, 41728 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene high mobility group box 2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in peptidyl-serine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in peptidyl-serine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    casein kinase I isoform gamma-3; casein kinase I
    Names
    CKI-gamma 3
    NP_690022.2
    XP_006526293.1
    XP_006526294.1
    XP_006526295.1
    XP_006526296.1
    XP_006526297.1
    XP_006526298.1
    XP_006526299.1
    XP_006526300.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152809.2NP_690022.2  casein kinase I isoform gamma-3

      See identical proteins and their annotated locations for NP_690022.2

      Status: VALIDATED

      Source sequence(s)
      AK032675, AK034842, AK049379, AK163441, BQ443928, BY729947, CN454971
      Consensus CDS
      CCDS37823.1
      UniProtKB/Swiss-Prot
      Q8C4X2
      Related
      ENSMUSP00000070259.7, ENSMUST00000069597.8
      Conserved Domains (2) summary
      cd14126
      Location:42329
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:329386
      CK1gamma_C; Casein kinase 1 gamma C terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      53995154..54088756
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526230.2XP_006526293.1  casein kinase I isoform X1

      See identical proteins and their annotated locations for XP_006526293.1

      Conserved Domains (2) summary
      cd14126
      Location:42329
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:329418
      CK1gamma_C; Casein kinase 1 gamma C terminal
    2. XM_006526233.2XP_006526296.1  casein kinase I isoform X4

      See identical proteins and their annotated locations for XP_006526296.1

      Related
      ENSMUSP00000158175.2, ENSMUST00000237880.2
      Conserved Domains (2) summary
      cd14126
      Location:42329
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:329418
      CK1gamma_C; Casein kinase 1 gamma C terminal
    3. XM_006526232.2XP_006526295.1  casein kinase I isoform X3

      Conserved Domains (2) summary
      cd14126
      Location:42329
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:329416
      CK1gamma_C; Casein kinase 1 gamma C terminal
    4. XM_006526236.1XP_006526299.1  casein kinase I isoform X7

      See identical proteins and their annotated locations for XP_006526299.1

      Conserved Domains (2) summary
      cd14126
      Location:42329
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:329386
      CK1gamma_C; Casein kinase 1 gamma C terminal
    5. XM_006526231.2XP_006526294.1  casein kinase I isoform X2

      Conserved Domains (2) summary
      cd14126
      Location:42328
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:328417
      CK1gamma_C; Casein kinase 1 gamma C terminal
    6. XM_006526234.2XP_006526297.1  casein kinase I isoform X5

      Conserved Domains (2) summary
      cd14126
      Location:42328
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:328417
      CK1gamma_C; Casein kinase 1 gamma C terminal
    7. XM_006526235.1XP_006526298.1  casein kinase I isoform X6

      Conserved Domains (2) summary
      cd14126
      Location:42328
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:328385
      CK1gamma_C; Casein kinase 1 gamma C terminal
    8. XM_006526237.1XP_006526300.1  casein kinase I isoform X8

      Conserved Domains (2) summary
      cd14126
      Location:42328
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:328385
      CK1gamma_C; Casein kinase 1 gamma C terminal
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